what does slight progression of degenerative marrow
in the l5 - s1
Discogenic marrow endplate changes at C5-6 refer to degenerative alterations in the vertebral endplate at that specific level of the cervical spine, likely due to wear and tear over time. This can lead to decreased disc height, altered biomechanics, and potentially contribute to symptoms such as neck pain or radiculopathy. Treatment may involve conservative measures like physical therapy, pain management, or in some cases, surgery.
Modic changes, a common observation in MR imaging, are signal intensity changes in vertebral body marrow, adjacent to the endplates of degenerative discs.Michael T. Modic, MD, professor of radiology and neurology at Case Western in Cleveland, wrote about these changes in the journal Radiology in 1988, and his name has been associated with these changes ever since.Modic changes take 3 main forms:Type I· Decreased signal on T1, and increased signal on T2.· Represents marrow edema.· Associated with an acute process.· Histological examination shows disruption and fissuring of the endplate and vascularized fibrous tissues within the adjacent marrowType II - the most common type· Increased signal on T1, and isointense or slightly hyperintense signal on T2.· Represents fatty degeneration of subchondral marrow.· Associated with a chronic process.· Histological examination shows endplate disruption with yellow marrow replacement in the adjacent vertebral body.Type I changes convert to Type II changes with time, while Type II changes seem to remain stable.Type III· Decreased signal on both T1 and T2.· Correlate with extensive bony sclerosis on plain radiographs.· Histological examination shows dense woven bone; hence, no marrow to produce MRI signal.MODIC CHANGES on MRIT1T2SignificanceTYPE 1¯­EdemaTYPE II­® (or slight­)Fatty DegenerationTYPE III¯¯Bony Sclerosis
Modic changes, a common observation in MR imaging, are signal intensity changes in vertebral body marrow, adjacent to the endplates of degenerative discs.Michael T. Modic, MD, professor of radiology and neurology at Case Western in Cleveland, wrote about these changes in the journal Radiology in 1988, and his name has been associated with these changes ever since.Modic changes take 3 main forms:Type I· Decreased signal on T1, and increased signal on T2.· Represents marrow edema.· Associated with an acute process.· Histological examination shows disruption and fissuring of the endplate and vascularized fibrous tissues within the adjacent marrowType II - the most common type· Increased signal on T1, and isointense or slightly hyperintense signal on T2.· Represents fatty degeneration of subchondral marrow.· Associated with a chronic process.· Histological examination shows endplate disruption with yellow marrow replacement in the adjacent vertebral body.Type I changes convert to Type II changes with time, while Type II changes seem to remain stable.Type III· Decreased signal on both T1 and T2.· Correlate with extensive bony sclerosis on plain radiographs.· Histological examination shows dense woven bone; hence, no marrow to produce MRI signal.MODIC CHANGES on MRIT1T2SignificanceTYPE 1¯­EdemaTYPE II­® (or slight­)Fatty DegenerationTYPE III¯¯Bony Sclerosis
Marrow edema and mild endplate findings could be inflammatory spondyloarthropathy. This could indicate anything from ankylosing spondylitis (AS)and back pain associated with psoriatic arthritis or inflammatory bowel disease (IBD).
Bone marrow edema in the cervical spine refers to a condition where there is swelling or fluid accumulation in the bone marrow of the cervical vertebrae. This can be caused by various factors such as injury, inflammation, or degenerative changes. It can lead to pain, stiffness, and decreased range of motion in the neck.
This condition is known in common terms as Dowager's Hump. It is an abnormal outward curvature of the vertebrae of upper back. It due osteoporosis changes in the thoracic spine and mostly affects postmenopausal women.
Red marrow hyperplasia is the increased production of red blood cells in the bone marrow. Heterogeneous marrow pattern narrowing replacing lesion refers to abnormal changes in the bone marrow, potentially indicating infiltration of malignant cells like in multiple myeloma. These findings suggest that the bone marrow of the spine is being affected by an infiltrative process, which could be indicative of multiple myeloma.
In adults, most bones contain yellow marrow (primarily fat).In children this is often red marrow (to generate blood cells), but changes to yellow marrow as we age.
Treatment for marrow edema in the L5 pedicle typically focuses on addressing the underlying cause, such as trauma or degenerative changes. Conservative management may include rest, physical therapy, and non-steroidal anti-inflammatory drugs (NSAIDs) to reduce pain and inflammation. In some cases, imaging follow-up may be necessary to monitor the condition. If symptoms persist or worsen, further evaluation or intervention, such as corticosteroid injections or surgery, may be considered.
Infants grow relatively fast and need quite a lot of red blood cells, which are only produced in red bone marrow. As the infants grow older, much of the red bone marrow is gradually replaced by yellow bone marrow containing a special kind of fat that gives it its yellowish color. If the body needs more red blood cells than the remaining red marrow is capable of producing, some of the yellow marrow changes to red marrow.
bone marrow
red marrow and yellow marrow...