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The renal system (kidneys) is the main regulator of both blood volume and blood salt concentration, but the two factors are regulated somewhat independently of each other as both the volume of urine produced and it's salt concentration vary with their own hormone system.

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What happen to urine volume when water intake is decreased?

The urine volume will decrease.


What happened to the urine volume as the concentration gradient increased?

As the concentration gradient increases, the urine volume typically decreases. This is because a higher concentration gradient drives more water reabsorption in the kidneys, resulting in a lower urine volume being produced.


What happend to the volume of urine as the solute concentration in the interstitial space was increased?

As the solute concentration in the interstitial space increases, the volume of urine produced by the kidneys typically decreases. This is because the higher solute concentration triggers the release of antidiuretic hormone (ADH), which increases water reabsorption in the kidneys, leading to a decrease in urine volume.


What effect would drinking water have on fluid handling in kidney?

Too much fluid intake will cause the kidneys to produce more urine and inadequate fluid intake will cause the kidneys to conserve body fluids by reducing the volume of urine excreted


What effect does the concentration gradient of the interstitial fluid have on the maximum urine concentration?

The concentration gradient of the interstitial fluid affects the osmolarity of the renal medulla. A steeper concentration gradient allows for more concentration of urine by the kidneys, as the gradient drives water reabsorption in the collecting ducts, leading to concentrated urine production.


If a tumor of the glucocorticoid-secreting cells of the adrenal cortex crowds out the cells that produce aldosterone what is the likely effect on urine composition and volume?

The tumor would cause increased secretion of glucocorticoids and decreased aldosterone production, leading to increased sodium and water retention in the kidneys. This would result in increased urine volume and decreased urine concentration, leading to dilute urine with low sodium levels.


Why does urine volume decrease as the gradient concentration increases?

As the concentration gradient increases, more water is reabsorbed by the kidneys, leading to concentrated urine with lower volume. This allows the body to conserve water and maintain proper electrolyte balance.


What happened to the volume of urine as the solute concentration in the interstitial space increased?

As the solute concentration in the interstitial space increases, the volume of urine tends to decrease. This is because the kidneys reabsorb more water from the filtrate to help maintain the body's fluid and solute balance.


What happen to urine volume if you did not add ADH to the collecting duct?

Without the presence of antidiuretic hormone (ADH), the permeability of the collecting duct to water decreases. As a result, more water is excreted in the urine, leading to a higher urine volume and lower urine concentration.


What are the factors affecting urine composition?

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How is the calculation of creatinine clearance from 24 hour urine collections done?

There is a special device called a toilet hat that you place in the toilet. It fits under the rim. You pee in it, take it out and empty it into a special collection jug set aside specifically for this purpose. After collection of the 24 hour excreted urine,creatinine clearance (CrCl) is calculated using the formula CrCl= (Ucr x V)/ (SrCr x t) where Ucr is creatinine concentration in urine V is volume of urine in ml SrCr is creatinine concentration in the serum and t is the time period of urine collection


What is the effect and mechanism of furosemide on urine volume?

Furosemide is a common diuretic drug given to lower the blood pressure by lowering volume. It does this by stimulating the kidneys to reabsorb less water and so uncreasing the urine output. The result is greater volume more dilute urine.