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When acetylcholine does not bind to muscle cells, it prevents the activation of nicotinic acetylcholine receptors at the neuromuscular junction. This failure to activate the receptors inhibits the influx of sodium ions, which is necessary for generating an action potential in the muscle fiber. Consequently, muscle contraction cannot occur, leading to muscle weakness or paralysis. This can happen in various conditions, such as myasthenia gravis or in the presence of certain toxins.
What else can I help you with?
Where does the acetylcholine released for muscle contraction bind?
Sarcolema receptors
What is the chemical transmitter released at the neuromuscular junction?
Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.
What effect does Curare have on muscle tissue?
It blocks the nicotinic cholinergic receptors on the muscle that normally bind the acetylcholine released by the motor neuron.
What effect will organopesticides have on muscle tissue?
Organopesticides will increase the severity of muscle contraction beyond normal conditions. Acetylcholine esterase inhibition will allow a more than normal amount of acetylcholine to bind to receptors.
What is the role of acetylcholine in skeletal muscle contractions?
acetylcholine as far as i know is a neurotransmitter that ativates the mscle cells.
What do you think the effect of breaking down acetylcholine is on muscle contraction?
Breaking down acetylcholine can lead to muscle relaxation because acetylcholine is a neurotransmitter that stimulates muscle contraction. When acetylcholine is broken down, the signal for muscle contraction is reduced, resulting in muscle relaxation.
What prevents acetylcholine from accumulating in the neuromuscular junction?
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
What chemical stimulates muscle contraction?
acetylcholine (ACh)
What type of excitatory neurotransmitter is secreted by motor neurons innervating skeletal muscle?
Acetylcholine is the excitatory neurotransmitter released by neurons innervating skeletal muscles. Acetylcholine release stimulates muscle contraction by acting at the nicotinic-acetylcholine receptor on the surface of the muscle cell.
What bind the muscle cells together?
tendons - bind muscle to muscle ligaments- bind muscle to bone
What are two types of receptors that bind acetylcholine?
nicotinic and muscarinic
When myosin cross bridges bind to actin what happens?
Muscle contraction results
