Secretin is a hormone that controls the secretions into the duodenum, and also separately, water homeostasis throughout the body. It is produced in the S cells of the duodenum in the crypts of Lieberkühn.[1] Its effect is to regulate the pH of the duodenal contents via the control of gastric acid secretion and buffering with bicarbonate from the centroacinar cells of the pancreas as well as intercalated ducts. It is notable for being the first hormone to be identified.[2] In humans, the secretin peptide is encoded by the SCT gene
Gastric inhibitory peptide (GIP) is a hormone produced in the small intestine that primarily functions to inhibit gastric motility and secretion. It plays a crucial role in regulating insulin release from the pancreas in response to the presence of fats and carbohydrates in the digestive tract. By slowing gastric emptying, GIP helps modulate nutrient absorption and maintain blood sugar levels. Additionally, it contributes to the overall coordination of digestive processes.
Cholecystokinin (CCK) is a peptide hormone that decreases gastric motility by inhibiting the stomach muscles from contracting. It is released in response to the presence of fatty acids and amino acids in the small intestine to slow down digestion and promote the feeling of fullness.
Secretin is a hormone produced by the S cells of the duodenum in response to acidic chyme entering the small intestine from the stomach. Its primary function is to stimulate the pancreas to release bicarbonate-rich fluid, which helps neutralize stomach acid, creating an optimal pH for digestive enzymes in the intestine. Additionally, secretin promotes bile production in the liver and regulates gastric acid secretion, contributing to overall digestive processes.
The hormone responsible for inhibiting the release of gastric juice is known as gastric inhibitory polypeptide.
The hormone secreted by cells in the stomach lining that increases gastric juice release is called gastrin. It is produced by G cells in the gastric mucosa and stimulates the secretion of gastric acid (HCl) from parietal cells, enhancing digestion. Gastrin also promotes gastric motility, facilitating the mixing and movement of food within the stomach.
a polypeptide hormone,
It is a hormone produced by stomach.Itg stimulates secretion of gastric juice.
control of gastroc secretion is divided to cephalic phase, gastric phase and intestinal phase. Among these, intestinal phase means gastric secretion in stomach as a result of stimulation in intestine by food. when the food reaches the intestine it secrete gastrin and the hormone transports to stomach by circulation. amount of secretion in intestinal phase is smaller and slower than that of cephalic and gastric phase. by the way if substance like acid, lipid or any high osmotic solution entered intestine, duodenum, gastric secretion decreases this time. This is because of enterogastrone released from duodenum. there are also other hormones such as cholecystokinin and gastric inhibitory peptide. they inhibit the secretion in stomach.
The original answer posted was Cholecystokinin, which is actually a peptide hormone that is released to inhibit gastric mobility. But it is not the first hormone to be released when fat or food initially contacts the duodenum.When Fat enters the duodenum, this accounts for the third phase of gastric secretion, called intestinal phase. This phase accounts for 5% of the total secretory response. It begins when food leaves the stomach and enters the small intestine (duodenum). When the food first contacts the intestinal wall, it stimulates intestinal cells to release a hormone called, intestinal gastrin, that enhances gastric gland secretion.
Somatostatin
Gastrin is the hormone that stimulates the opening of the pyloric sphincter. It is secreted by the stomach in response to the presence of food and stimulates the release of gastric acid as well as the relaxation of the pyloric sphincter to allow food to pass from the stomach to the small intestine.
The hormone released when a person eats is gastrin. Gastrin stimulates the stomach to produce gastric acid and enzymes, which help break down food for digestion. This process aids in the absorption of nutrients in the small intestine.