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Hemoglobin produced in association with the sickle cell trait; the beta-globin molecules of hemoglobin S are defective.

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14y ago

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What is the molecular basis for the difference in the electrophoretic pattern between normal hemoglobin A and hemoglobin S?

The difference in electrophoretic pattern between normal hemoglobin A and hemoglobin S is due to a single amino acid substitution. In hemoglobin S, a glutamic acid is replaced by a valine at position 6 of the beta-globin chain. This change causes hemoglobin S to have a different charge, leading to its characteristic migration pattern on electrophoresis.


What is the hemoglobin pigment for?

hemoglobin is what give the red blood cells it,s clour


Hemoglobin S differs from hemoglobin A in that?

glutamic acid is replaced by valine in the beta chain


What is the Life span for hemoglobin SC disease or hemoglobin S beta thalassemia?

4 months


Is hemoglobin s the same thing as hemoglobin solubility?

Hemoglobin S refers to the hemoglobin that forms in patients with sickle cell anemia. Hemoglobin solubility is a test that can be performed in order to determine if the patient has sickle cell anemia.


What has the author H Lehmann written?

H. Lehmann has written: 'Human haemoglobin variants and their characteristics' -- subject(s): Hemoglobin, Tables 'Man's haemoglobins' -- subject(s): Hemoglobin, Hemoglobinopathy


Which Stains are used for staining globin chains of hemoglobin?

Hemoglobin electrophoresis uses stains such as Coomassie blue or Ponceau S to visualize the globin chains of the hemoglobin molecule. These stains help separate and identify different types of hemoglobin based on the migration pattern of the globin chains.


Why hemoglobin s is not soluble?

Hemoglobin S is not soluble due to its abnormal structure, which results from a mutation in the beta-globin gene. This mutation causes the hemoglobin molecules to polymerize under low oxygen conditions, leading to the formation of rigid, sickle-shaped red blood cells. These sickled cells are less flexible and can cause blockages in blood vessels, resulting in various complications associated with sickle cell disease. The insolubility of hemoglobin S is a key factor in the pathology of this condition.


Daughter and son both are low in hemoglobin dr said that they may have either hemoglobin ACF or S what test should you ask dr to perform on your kids?

Do hemoglogin electrophoresis


Is a hemoglobin a hormone?

A hemoglobin is a red protein responsible for transporting oxygen in the blood of vertebrates. Its molecule comprises four subunits, each containing an iron atom bound to a heme group. TO answer your question. THe answer is a big, fat "NO".


What part of the blood cell carries oxygen?

hemoglobin


What has the author Robert M Winslow written?

Robert M. Winslow has written: 'Advances in Blood Substitutes' 'Hemoglobin-based red cell substitutes' -- subject(s): Blood Substitutes, Hemoglobin