A carrier of thalassemia, often referred to as having thalassemia trait, is an individual who possesses one normal hemoglobin gene and one mutated gene associated with thalassemia. This genetic condition typically does not cause significant health issues, but carriers can pass the mutated gene to their offspring. If both parents are carriers, there is a risk of having children with more severe forms of thalassemia, which can lead to serious health complications. Testing for thalassemia carriers is important for family planning and genetic counseling.
Yes, A "carrier" of alpha thalassemia and of beta thalassemia can marry, but not to someone with any hemoglobinopathy. Prof. Kornfeld Pal
If you have Thalassemia major but your boyfriend is not a carrier then the child will be born a healthy carrier (thalassemia minor) but shouldn't need blood transfusions. If your boyfriend is a carrier then you would have a 50% chance of having a child with thalassemia major like you do.
yes
The Thalassemia Major person marries a normal person then 50% chance of getting normal or else 50% chance is the child will be Thalassemia Carrier / Minor. So, not to be worried to go ahead with production. with regards rajesh popli
i was told many years ago that i couldn't donate as I'm a beta thalassemia carrier. best to ask your local donation center.
Yes, a person with hemoglobin E trait can marry a beta thalassemia carrier. However, it is important for both individuals to undergo genetic counseling to understand the potential risks for their children. They could have offspring with various combinations of hemoglobin disorders, including hemoglobin E disease or beta thalassemia. Genetic testing can help assess the likelihood of these outcomes.
Id like to know this aswel. Does anyone know please?
If only the mother has the thalassemia trait, each child has a 50% chance of inheriting the trait and becoming a carrier, and a 50% chance of being unaffected. The father’s genotype will determine the overall risk for the children. If the father does not have thalassemia or the trait, the children will only be carriers. However, if the father also carries the trait, there is a possibility of having children with thalassemia disease.
If one parent is a carrier then the baby has a 50% chance of being born a carrier as well, but the baby will be healthy as the gene is recessive.
Yes, a man can pass thalassemia to his offspring if he carries a gene for the disorder. Thalassemia is inherited in an autosomal recessive manner, meaning that a child must inherit two copies of the mutated gene (one from each parent) to be affected. If the man has one copy of the thalassemia gene, he can pass it to his child, who may then be a carrier or affected if the other parent also carries the gene.
you have a 50/50 chance me and my twin both had it and my 2 older brothers are fine 1 is a carrier and the other is not.
Yes, a silent carrier of alpha-thalassemia can have macrocytes, although it is not common. Macrocytosis typically occurs when there is an underlying deficiency in vitamin B12 or folate, but it can also be seen in some cases of thalassemia due to ineffective erythropoiesis. In silent carriers, the impact on red blood cell morphology is usually mild, but variations can occur based on individual genetic and environmental factors. Regular monitoring and further testing are advised if macrocytic anemia is suspected.