yes
Yes, A "carrier" of alpha thalassemia and of beta thalassemia can marry, but not to someone with any hemoglobinopathy. Prof. Kornfeld Pal
If you have Thalassemia major but your boyfriend is not a carrier then the child will be born a healthy carrier (thalassemia minor) but shouldn't need blood transfusions. If your boyfriend is a carrier then you would have a 50% chance of having a child with thalassemia major like you do.
Yes, a person with hemoglobin E trait can marry a beta thalassemia carrier. However, it is important for both individuals to undergo genetic counseling to understand the potential risks for their children. They could have offspring with various combinations of hemoglobin disorders, including hemoglobin E disease or beta thalassemia. Genetic testing can help assess the likelihood of these outcomes.
Alpha thalassemia silent carrierAlpha thalassemia minor, also called alpha thalassemia traitHemoglobin H diseaseAlpha thalassemia major, also called hydrops fetalisBeta thalassemia minor, also called beta thalassemia traitBeta thalassemia intermediaBeta thalassemia major, also called Cooley's anemia or beta-zero (ß0) thalassemiaBeta-plus (ß+) thalassemiaMediterranean anemia
Yes, a silent carrier of alpha-thalassemia can have macrocytes, although it is not common. Macrocytosis typically occurs when there is an underlying deficiency in vitamin B12 or folate, but it can also be seen in some cases of thalassemia due to ineffective erythropoiesis. In silent carriers, the impact on red blood cell morphology is usually mild, but variations can occur based on individual genetic and environmental factors. Regular monitoring and further testing are advised if macrocytic anemia is suspected.
Thalassemia is classified mainly into two types: alpha thalassemia and beta thalassemia, based on which globin chain is affected. Alpha thalassemia occurs due to mutations in the alpha-globin genes, while beta thalassemia results from mutations in the beta-globin genes. Each type can further be categorized into various subtypes based on the severity of the condition, such as thalassemia minor (trait) and thalassemia major (Cooley's anemia). The classification helps determine the appropriate management and treatment strategies for affected individuals.
have seen one of my friends sister had kid and all normal no complications...not thalassemia either.........beta and alpha i think there is 25% normal chance
A carrier of thalassemia, often referred to as having thalassemia trait, is an individual who possesses one normal hemoglobin gene and one mutated gene associated with thalassemia. This genetic condition typically does not cause significant health issues, but carriers can pass the mutated gene to their offspring. If both parents are carriers, there is a risk of having children with more severe forms of thalassemia, which can lead to serious health complications. Testing for thalassemia carriers is important for family planning and genetic counseling.
It is unlikely.
The Thalassemia Major person marries a normal person then 50% chance of getting normal or else 50% chance is the child will be Thalassemia Carrier / Minor. So, not to be worried to go ahead with production. with regards rajesh popli
Of coare yes. You can get any hemoglobinopathy from a parent without any connection to other hemoglobinopathy (or any other hereditary disease) from the other parent. Prof. Kornfeld Pal
i was told many years ago that i couldn't donate as I'm a beta thalassemia carrier. best to ask your local donation center.