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Do antigen presenting cells have major histocompatibility complex class I molecules?
Yes, antigen presenting cells have major histocompatibility complex class I molecules.
What cell is not and antigen presenting cell?
Red blood cells are not antigen presenting cells because they lack major histocompatibility complex (MHC) molecules, which are required for presenting antigens to T cells.
What is the type of major histocompatibility marker that's most likely found on a liver cell?
Answer Class II MHC protein. Class II are found in membranes of antigen-presenting cells-phagocytic cells and lymphocytes. The liver performs phagocytosis and antigen presentation.
What has the author Woong-Kyung Suh written?
Woong-Kyung Suh has written: 'Interaction of Class I major histocompatibility molecules with the transporter associated with antigen processing, (TAP) and the molecular chaperone calnexin'
What is the first signal required for activation of a T cell?
The first signal required to activate a T cell is MHC(Major Histocompatibility Complex) presenting an antigen(foreign peptide) to the T cell receptor.
The function of an antigen-presenting cell depends on the presence of what?
The function of an antigen-presenting cell depends on the presence of major histocompatibility complex (MHC) molecules, which provide a platform for presenting antigens to T cells. Additionally, the presence of co-stimulatory molecules is crucial for activating T cells and initiating an immune response.
What has the author Jan Klein written?
Jan Klein has written: 'Natural history of the major histocompatibility complex' -- subject(s): Major histocompatibility complex, HLA histocompatibility antigens, Histocompatibility 'Immunology' -- subject(s): Allergy and Immunology, Immune system, Immunity, Immunology, Physiology 'Neuroimaging'
Do T cells have major histocompatibility complex (MHC) molecules?
Yes, T cells have major histocompatibility complex (MHC) molecules.
What is another term for histocompatibility testing?
tissue typing
What is an isoantigen?
An isoantigen is an antigen that is found on the cells of one individual but not on the cells of another individual within the same species. These antigens can trigger an immune response when cells from different individuals are mixed, and are important in determining compatibility for blood transfusions and organ transplants. They are primarily determined by differences in the major histocompatibility complex (MHC) genes between individuals.
Antigen presentation is essential for the activation and clonal selection of what?
Antigen presentation is essential for the activation and clonal selection of T cells, particularly CD4+ helper T cells and CD8+ cytotoxic T cells. Antigen-presenting cells (APCs), such as dendritic cells, macrophages, and B cells, process and present antigens on their surface using major histocompatibility complex (MHC) molecules. This interaction, along with co-stimulatory signals, initiates T cell activation, leading to proliferation and differentiation into effector cells. This process is crucial for the adaptive immune response against pathogens.
What are the double signals in T cell activation?
T cells receive 3 signals during activation:1. Major Histocompatibility Complex (MHC) presenting an antigen (foreign peptide) to the T cell receptor2. The co-stimulatory signal (B7 on the dendritic cell binding to CD28 on the T cell)The first signal ensures that the T cell is specific for the antigen it has been presented.The T cell cannot be activated without also recieveing the second signal. This is how the T cell checks that it has been presented an antigen by a "professional" antigen presenting cell.3. Cytokines (signalling molecules) are released by the dendritic cell - these cause the differentiation of the T cell
