In the US, that would be the vaccine used in the H1N1/09 nasal spray vaccinations. These weakened viruses used to make that nasal vaccine are called attenuated, which means weakened. The weakening is usually done with chemicals. People aged 2 to 49 can use this nasal spray vaccine. Those younger or older should use the flu shots which are made with inactivated ("dead") viruses.
A vaccination using a vaccine made from attenuated live viruses.
Live vaccines contains weakened viruses of the disease. These viruses can not cause the disease but give immunity to the recipient. ( In the initial days of such trials, 18 patient got the rabies due to vaccine and died.)
They are called live attenuated vaccines. Attenuated means weakened. The nasal mist flu vaccine is an example of a live attenuated vaccine. The vaccines for flu that are injected are made from pieces of viruses or "dead" viruses. See the related question below for more information on these two types of vaccines.
Attenuated simply means "weakened". An attenuated flu vaccine refers to vaccines made with live viruses (so you get a good immune response), but they have been weakened chemically so that they are unable to give you the flu. There are two types of flu vaccines available in the US. What is called inactivated, inactive or "dead" vaccine and what is called "live", weakened/attenuated vaccine. The injectable vaccines (intradermal and intramuscular) are made with "dead" viruses and the nasal spray is made with "live" attenuated viruses.
TB vaccine is a live attenuated vaccine (LAV). This type of vaccine prepared from living micro-organisms (viruses, bacteria currently available) that have been weakened under laboratory conditions.LAV vaccines will replicate in a vaccinated individual and produce an immune response but usually cause a mild or no disease.
No. This is not possible. The Gardasil vaccine contains recombinant proteins from HPV to provoke an immune response. There are no live viruses, attenuated viruses or even dead viruses in the vaccine. The viral DNA is not present in any form.
The best example of an attenuated live vaccine is the measles, mumps, and rubella (MMR) vaccine. This vaccine contains live viruses that have been weakened (attenuated) so they cannot cause disease in healthy individuals but still elicit a strong immune response. Other examples include the yellow fever vaccine and the oral polio vaccine. These vaccines stimulate long-lasting immunity without causing the diseases they protect against.
The active ingredient is the live, attenuated (weakened) measles virus.
An attenuated vaccine contains live, weakened microbes. These will multiply at a very low rate in the body but will not cause disease symptoms. This low reproduction rate will allow the body's immune defense to produce an antigen to the pathogen. Because they are live and very close to the natural pathogen, the immunity built from this vaccine generates the strongest immune response.
There are a few circumstances that can create some risk of getting the virus, such as in people whose immune systems aren't working right (e.g., they recently had cancer chemotherapy or HIV or some other immuno-suppressive disorder). See the list of people in the related question below who should not get vaccinated with the types of vaccines that contain a live "attenuated" virus. Attenuated means weakened. When someone has a weak immune system, they may be susceptible to the weakened form of virus in the vaccine. But they would not be able to be sick from getting vaccines that contain "dead" viruses. With the flu vaccines, for example, the shots have dead viruses in them but the nasal mist has live attenuated viruses in it.Sometimes. If the vaccine is a live attenuated (weakened) vaccine, then you get a dose of virions (viral particles/viruses) that are no longer dangerous to humans as they have been weakened so they can not make you sick. Other vaccines (such as Gardasil) are made with Virus-like particles (VLP) and these are just pieces of the virus (such as the envelope) not actually working and replicating viruses so they can not make you sick either.
Live attenuated vaccines are typically not given to people with compromised immune systems because they contain weakened forms of the virus that may still cause illness in those with weakened immune responses.
With influenza vaccinations, if the child had the vaccine given by injection (flu shot) and not by nasal spray, then the vaccine would have been made from inactivated viruses and not from weakened, but still live, viruses. The live virus vaccines are the ones that have potential infection problems for the immunocompromised person.