They are called live attenuated vaccines. Attenuated means weakened. The nasal mist flu vaccine is an example of a live attenuated vaccine. The vaccines for flu that are injected are made from pieces of viruses or "dead" viruses. See the related question below for more information on these two types of vaccines.
Live vaccines contains weakened viruses of the disease. These viruses can not cause the disease but give immunity to the recipient. ( In the initial days of such trials, 18 patient got the rabies due to vaccine and died.)
An attenuated vaccine contains live, weakened microbes. These will multiply at a very low rate in the body but will not cause disease symptoms. This low reproduction rate will allow the body's immune defense to produce an antigen to the pathogen. Because they are live and very close to the natural pathogen, the immunity built from this vaccine generates the strongest immune response.
TB vaccine is a live attenuated vaccine (LAV). This type of vaccine prepared from living micro-organisms (viruses, bacteria currently available) that have been weakened under laboratory conditions.LAV vaccines will replicate in a vaccinated individual and produce an immune response but usually cause a mild or no disease.
Vaccines can contain either dead (inactivated) or weakened (live attenuated) forms of pathogens. Inactivated vaccines use pathogens that have been killed, rendering them unable to cause disease, while live attenuated vaccines use weakened forms that can still replicate but do not typically cause illness in healthy individuals. Both types stimulate the immune system to recognize and fight off future infections. The choice of vaccine type depends on the disease and the desired immune response.
No, in the US the injection forms of the vaccines are made from inactivated "dead" virus. The nasal spray vaccine contains weakened virus that can not make you get the flu but is called a Live Attenuated Influenza Vaccine (LAIV). There is a new form of injected vaccine for the flu in the 2011-2012 flu season in the US that is intradermal instead of the intramuscular route, it also contains inactivated virus particles. See the related question below.
A vaccination using a vaccine made from attenuated live viruses.
The best example of an attenuated live vaccine is the measles, mumps, and rubella (MMR) vaccine. This vaccine contains live viruses that have been weakened (attenuated) so they cannot cause disease in healthy individuals but still elicit a strong immune response. Other examples include the yellow fever vaccine and the oral polio vaccine. These vaccines stimulate long-lasting immunity without causing the diseases they protect against.
Live attenuated vaccines are typically not given to people with compromised immune systems because they contain weakened forms of the virus that may still cause illness in those with weakened immune responses.
Attenuated simply means "weakened". An attenuated flu vaccine refers to vaccines made with live viruses (so you get a good immune response), but they have been weakened chemically so that they are unable to give you the flu. There are two types of flu vaccines available in the US. What is called inactivated, inactive or "dead" vaccine and what is called "live", weakened/attenuated vaccine. The injectable vaccines (intradermal and intramuscular) are made with "dead" viruses and the nasal spray is made with "live" attenuated viruses.
The active ingredient is the live, attenuated (weakened) measles virus.
In the US, that would be the vaccine used in the H1N1/09 nasal spray vaccinations. These weakened viruses used to make that nasal vaccine are called attenuated, which means weakened. The weakening is usually done with chemicals. People aged 2 to 49 can use this nasal spray vaccine. Those younger or older should use the flu shots which are made with inactivated ("dead") viruses.
A suspension of killed or live-attenuated microorganisms is referred to as a vaccine. Vaccines are used to stimulate the immune system to provide protection against specific pathogens by inducing an immune response without causing the disease.