Cushing's Syndrome
"Cushing" refers to Cushing's syndrome, an issue that results from high exposures to the hormone cortisol. The syndrome will result in a tumor appearing on the pituitary gland.
The most common cause for Cushing's syndrome is iatrogenic, meaning it is a side effect of a medication given by their doctor, but it could also be caused by Cushing's disease (a pituitary adenoma), adrenal gland tumors, or due to hormones secreted by certain types of cancers.
Cushing's syndrome is a rare condition caused by prolonged exposure to high levels of cortisol. It does not typically result in death directly, but complications related to the condition such as heart disease, infections, or organ failure can lead to mortality. The exact number of deaths specifically attributed to Cushing's syndrome per year is unknown.
Yes, it can. Search online for information related to Cushing's Diease (pituitary-originated), and Cushing's Syndrome (adrenal-originated). Cushing's is an over-production of Cortisol, which can result in many, different, seemingly unrelated symptoms. If you believe you have Cushing's see your primary care physician or an endocrinologist for help.
Cushing's syndrome is primarily caused by an excess of cortisol in the body, which can result from various factors. The most common cause is a pituitary adenoma that leads to increased production of adrenocorticotropic hormone (ACTH), stimulating the adrenal glands to produce more cortisol. It can also be caused by adrenal tumors or ectopic ACTH production from tumors elsewhere in the body. Additionally, long-term use of corticosteroid medications can induce Cushing's syndrome.
High levels of circulating cortisol, due to administration of doses of glucocorticoids over a span of time, can result in a condition known as Cushing's syndrome.
High levels of circulating cortisol, due to administration of doses of glucocorticoids over a span of time, can result in a condition known as Cushing's syndrome.
Pathological hypercortisolemia, or Cushing's syndrome, named after the United States surgeon, Harvey Cushing (1869-1939), may result from a lung cancer , tumor of the pituitary or adrenal glands, or from kidney failure.
Pathological hypercortisolemia, or Cushing's syndrome, named after the United States surgeon, Harvey Cushing (1869-1939), may result from a lung cancer , tumor of the pituitary or adrenal glands, or from kidney failure.
Patients with Cushing disease have a tumor that secretes a hormone called corticotropin (also called adrenocorticotropic hormone, or ACTH). ACTH is a hormone normally produced by the body (specifically the part of the brain called the pituitary gland) and acts on the adrenal glands, causing them to produce a hormone called cortisol. Cortisol is an important stress hormone that has a number of effects on the body.The ACTH-producing tumor of Cushing disease results in excessively high levels of cortisol in their bloodstream. The cortisol acts throughout the body, causing a redistribution of fat (causing abdominal obesity and two conditions called "moon facies" and "buffalo hump"), thinning of the skin (leading to skin lesions called striae), bone weakness, high blood glucose (which can lead to diabetes), and other conditions.This collection of signs and symptoms is called Cushing syndrome, which is distinct from Cushing disease. Cushing syndrome can be seen in any circumstance where the levels of cortisol are elevated; this frequently happens in patients that are taking cortisol prescribed by their doctor. Cushing disease is excess cortisol caused by an ACTH-secreting tumor.Cushing's disease mainly refers to the manifestation of Cushing's syndrome which is the result of a pituitary gland tumour. The lower portion of the brain has the pituitary gland which controls cortisol production within the body. One of the important causes of this disease could be the small tumours which may cause the adrenal glands to produce too much cortisol resulting in significant changes to the body. In reality, the tumours are not said to be typically malignant or cancerous but if enlarged may lead to vision impairment.
- Alkali ingestion, such as antacids or bicarbonate - Vomiting, which may result in the loss of too much H+ - Constipation, which may result in reabsorption of elevated levels of HCO3-