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Cholesterol synthesis primarily occurs in the liver and involves a complex series of enzymatic reactions, starting from acetyl-CoA and culminating in the production of cholesterol. This process is tightly regulated by various factors, including dietary intake, hormonal signals, and feedback mechanisms from cholesterol levels themselves. Excess cholesterol can be converted into bile acids or stored in lipid droplets, while low levels trigger increased synthesis and uptake from dietary sources. Overall, cholesterol plays vital roles in cell membrane structure, hormone production, and lipid metabolism.

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2w ago

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Well, cholesterol bio-synthesis is controlled by the regulation of HMG-CoA Reductase. This happens near the beginning of the pathway, so in my opinion would seem to be the key step in the process. There are actually 5 steps considered to be the bio-synthesis pathway of cholesterol. They all seem to me as important but it's just my opinion. Hope it helps.