It is used in the treatment of overactive bladder, with symptoms of urinary urge incontinence.
Solifenacin is used to treat overactive bladder with symptoms such as urinary incontinence, urinary frequency as well as urinary urgency. It reduces muscle spasms of the urinary tract and bladder.
The trademark name is Vesicare, styled as VESIcare(solifenacin succinate), a continence control drug.
Long-term use of solifenacin succinate, an anticholinergic medication used to treat overactive bladder, can lead to several negative effects. These may include cognitive impairment, particularly in older adults, as well as an increased risk of dementia. Other potential issues include urinary retention, constipation, and dry mouth, which can significantly affect quality of life. Additionally, prolonged use may lead to tolerance, reducing the drug’s effectiveness over time.
Medications can reduce many types of leakage. Some drugs inhibit contractions of an overactive bladder. Others, such as solifenacin succinate (Vesicare), relax muscles, leading to more complete bladder emptying during urination.
Malonate is a competitive inhibitor preventing the substrate succinate from binding to the enzyme. The structure of succinate is comparable to that of malonate but for the ability for malonate to bind to an enzyme but then cannot further act on it creating a nonproductive complex.
No. It won't be harmful if you do so, but you'll lose all solifenacin specificity on drug receptors. You'll get all oxybutinine side effects, without getting a benefit from using solifenacin. You should use higher dose of oxybutinine, or solifenacin alone. If you don't get enough effect from solifenacin, you should increase the dose to 10mg, or change for another medication.
Yes, you can take antacids with solifenacin, but it's important to space them out. Antacids can affect the absorption of solifenacin if taken together, so it's recommended to take solifenacin at least 2 hours before or after taking an antacid. Always consult with your healthcare provider for personalized advice.
Yes, solifenacin and omeprazole can typically be taken together, as there are no major interactions between the two medications. Solifenacin is used to treat overactive bladder, while omeprazole is a proton pump inhibitor used for acid-related conditions. However, it's always important to consult with a healthcare provider before combining medications to ensure safety and effectiveness based on individual health circumstances.
what is ammonium succinate? An amino acid
Malonate is a competitive inhibitor of succinate dehydrogenase, the enzyme responsible for converting succinate to fumarate in the citric acid cycle. Malonate resembles succinate and competes for the active site of succinate dehydrogenase. As a result, malonate binds to the enzyme and prevents succinate from binding, inhibiting the conversion of succinate to fumarate.
A succinate reaction refers to a chemical reaction involving succinate, a dicarboxylic acid, typically in metabolic pathways such as the citric acid cycle. In these reactions, succinate is converted into other compounds through a series of enzymatic steps.
Is dolxylamine succinate a drug they look for when drug testing.
All through the Citric Acid Cycle. Succinate dehydrogenase oxidizes succinate.