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This is the theoretical maximum volume of oxygen capable of binding to one gm of hemoglobin (Hb) multiplied by the % saturation of the hemoglobin. Practically, if one knows the amount of Hb per volume of blood then one can determine the volume of O2 carried by blood solely by Hb. Let us assume the following values:

[Hb] = 15gm/100mL

O2 bound per gm of Hb = 1.39 mL

and O2 saturation = 97.5%...

Then

O2 carrying capacity of 100 mL blood due to Hb = 15 x 1.39 x 0.975

= 20.33 mL O2/100mL

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