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The best anticoagulant for blood culture is sodium polyanethol sulfonate (SPS), which is commonly used in blood culture bottles. SPS inhibits the action of complement and phagocytes, helping to preserve microbial viability during culture. It is important to use the correct concentration to avoid inhibiting the growth of certain bacteria. Other anticoagulants, such as EDTA or citrate, are generally not recommended for blood cultures as they can adversely affect the growth of pathogens.

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1mo ago

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