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What is the different between Iron Deficiency Anemia and B12 deficiency and how can you tell the differences in a patient when they both show similar signs?
Iron deficiency anaemia - as the name suggests - is caused by the lack of sufficient iron.
Iron, inside the heme group of the protein Haemoglobin, is necessary to carry Oxygen (and carbon dioxide) inside the red blood cells. If the body tissues are not getting enough oxygen - hypoxia -, anaemia results.
The reasons can be:
- low dietary intake of heme iron (heme iron is easier to absorb)
- malabsorption (prevention of iron absorption)
- blood loss (iron lost along with the red blood cells)
- increased demand (rapid growth, pregnancy, lactation)
Vitamin B12 deficiency can also result in anaemia.
The reasons can be:
- Vitamin B12 deficiency
- folate deficiency
- liver disease/cirrhosis
- pregnancy
- myelodysplastic syndromes.
Since anaemias (hypoxia) symptoms generally are the same, diagnosis is based on blood film (blood smear), and blood tests' results of
- Hct = percentage of Red blood cells on whole blood,
- RCC = red blood cell count,
- MCV = Mean cell or corpuscule volume,
- MCH = Mean Corpuscular Haemoglobin,
- MCHC Mean corpuscular haemoglobin concentration, and also
- Serum iron (SI)
- Serum ferritin,
- Transferrin saturation,
- Total Iron binding Capacity (TIBC) .
Iron deficiency anaemia:
- Red blood cells are hypochromic (paler) and microcytic (smaller), due to less then normal contents of haemoglobin.
- Target cells,
- elliptocytes (pencil cells)
Vitamin B12 deficiency:
- Macrocytes (bigger red blood cells, due to delayed release from bone marrow)
(Macrocytes are often associated with Macrocyic Anaemia, too)
- Target cells,
- stomatocytes
- hypersegmented neutrophils.
Haemoglobin level in both cases are decreased, but MCV (Mean cell volume) is
- down in iron deficiency anaemia and
- up in Vitamin B12 deficiency (Macrocytic anaemia).
- ferritin level is always low in iron deficiency anaemia.
What else can I help you with?
What is the difference between primary and secondary vitamin deficiency?
what is the difference between primary and seconday vitamin deficiency
How common is AAT-deficiency?
It is estimated that there are between 75,000 and 150,000 Americans who were born with AAT-deficiency
Explain how loan supports and deficiency payments work?
Deficiency payments are government payments to compensate farmers for all or part of the difference between producer prices
What is progestrone deficiency and how to treat it?
For a good balanced sexual life both men and women are in need of progesterone hormone in good amount of number. If there is deficiency in progesterone hormone means then sexual life between men and women will become an unbalanced one. To reduce progesterone deficiency, progesterone cream for men and women are available which will be helpful for progesterone deficiency.
Is long time lapse between the nutritional deficiency and the clinical symptoms of a limitation of Nutritional Assessment?
Nutritional deficiency and its symptoms A list of essential Nutrients, incidence of its deficiency and the typical symptoms and diseases are given.Nutrition disorder wicked , the free encyclopedia. These include, but are not limited to , deficiency diseases, caused by a lack of essential nutrition naves disorders , symptoms sign/eponymous.
What is the difference between malnutrition maramus and kwashiorkor?
kwashiorkor is a syndrome due to severe protien deficiency whereas maramus (marasmus) is a syndrome due to a deficiency in both protien and calories.
Differentiate between the terms negative iron balance latent iron deficiency iron deficient erythropoiesis and iron deficiency anaemia?
Iron deficiency is body iron stores below the normal level as reflected by serum ferritin level of less than 12 ng/ ml, while iron deficient erythropoiesis mean that erythrocytes are produced deficient in iron or hypochromic. and iron deficiency anemia is the final step of uncorrected iron deficiency that is overt iron deficiency manifested by decreased hemoglobin level below normal (females < 12 g/dl, males < 14 g/ dl)
Every action and emotion has a mean a deficiency and an excess True of False?
True. This is the concept of the Golden Mean in Aristotle's philosophy, which suggests that virtuous behavior lies between extremes of deficiency and excess.
What indicates the inability to distinguish between color such as red and green?
The condition is called color deficiency.
In Arizona is there a deficiency balance owed by the seller on real property in a short sale?
I thought that Arizona was a non-deficiency state, but when the bank accepted my offer they alerted me that they would be coming after me for the difference between the sale price and what I owe (which is over $100k). They said that if the house was sold for less than 90% of what you owe, than they have authorization to come after you for the deficiency.
What is the most common nutrient deficiency in plants?
The most common nutrient deficiency in plants is usually nitrogen. Nitrogen is essential for plant growth and is a key component in chlorophyll, which is necessary for photosynthesis. Symptoms of nitrogen deficiency include yellowing of leaves and stunted growth.
Is New Jersey a deficiency judgment state?
Deficiency Judgments Deficiency judgments are permitted in New Jersey. A lawsuit for a deficiency must be commenced within three months from the date of the foreclosure sale, or confirmation of the sale if confirmation was required. Although the deficiency suit is a separate lawsuit, it can only be brought against a person who was joined to the foreclosure lawsuit and who is personally responsible for the mortgage debt. Such a person must be served with the process. On a note that is dated on or after May 1,1980, the debtor may dispute the deficiency by introducing evidence of the fair market value of the mortgaged premises at the time of the foreclosure sale. The deficiency is limited to the difference between the fair market value of the premises and the balance due on the loan. However, a borrower should object to the foreclosure sale price prior to the confirmation of the sale. The failure to do so may set the borrower up for a larger deficiency. However, some New Jersey courts are refusing to confirm the foreclosure sale unless the lender agrees, as part of the confirmation, not to sue the borrower for a deficiency greater than the difference between the fair market value and the balance owed on the loan.
