Serum Urea level 2.5 -7.8 mmol/L
The concentration of urea is high in urine because urea is a waste product produced by the liver when it breaks down proteins. The kidneys then filter urea from the blood and excrete it in urine to maintain the body's nitrogen balance.
urea
urea
(amino acid (grams)/ 6.25)-(UUNg (urine urea nitrogen) +4g)
The concentration of urea in urine is higher than in the filtrate due to the processes of reabsorption and secretion that occur during kidney function. As the filtrate passes through the renal tubules, water and various solutes are reabsorbed back into the bloodstream, concentrating the remaining substances, including urea. Additionally, urea can be secreted into the tubules from the blood, further increasing its concentration in the urine. This selective reabsorption and secretion ensure that waste products are efficiently excreted while conserving necessary substances.
During reabsoption most of the water exits the nephron and enters the interstitial fluid. This increases the concentration of ions such as potassium in the nephron. In the collecting duct (at the very end) very little water is left and the concentration of potassium, sodium, etc ions rises (including urea). This is why urine is acidic.
The maximum concentration of urea in human urine can vary, but it typically ranges between 600 to 1,200 milligrams per deciliter (mg/dL). Factors such as hydration status, diet, and overall health can influence these levels. In concentrated urine, especially during dehydration, urea concentrations can exceed this range.
Urea and Water.
Urea concentration is higher in urine than in the filtrate because the kidneys reabsorb water and certain solutes during the filtration process. As the filtrate passes through the renal tubules, water is reabsorbed, concentrating the remaining solutes, including urea. Additionally, urea is actively secreted from the blood into the tubular fluid, further increasing its concentration in the final urine. This process helps regulate nitrogen waste excretion while conserving water.
No, urea is a normal constituent of urine and is produced as a result of protein breakdown in the body. It is excreted by the kidneys as a way to eliminate waste products from the body.
The calculation of 24-hour urine urea nitrogen (UUN) is done by collecting all urine produced in a 24-hour period. The total volume of urine is measured, and a sample is analyzed for urea nitrogen concentration, usually using a laboratory method like spectrophotometry. The total UUN is then calculated by multiplying the concentration of urea nitrogen (in mg/dL) by the total urine volume (in dL) collected over the 24 hours. This value is important for assessing protein intake and nitrogen balance in clinical settings.
The normal glucose concentration in urine ranges from 0 to 15 mg/dL. The glucose concentration in urine becomes zero when no glucose has spilled over into the urine.