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substance in blood and tissues which, in the presence of ionized calcium, aids in the conversion of prothrombin to thrombin. Extrinsic and intrinsic thromboplastin are formed as the result of the interaction of different clotting factors; the factors that combine to form extrinsic thromboplastin are not all derived from intravascular sources, whereas those that form intrinsic thromboplastin are.

  • activated partial t. time - see http://www.answers.com/topic/activated-4 partial thromboplastin time.
  • extrinsic t. - the prothrombin activator formed as a result of interaction of coagulation factors III, VII, and X which, with factor IV, aids in the formation of thrombin.
  • t. generation time (TGT) - evaluates the first stage in blood coagulation by measuring the efficiency of prothrombinase formation.
  • intrinsic t. - the prothrombin activator formed as a result of interaction of coagulation factors V, VII, IX, X, XI and XII and platelet factor 3 (PF-3), which, with factor IV, aids in the conversion of prothrombin to thrombin.
  • plasma t. antecedent (PTA) - http://www.answers.com/topic/clotting-1 factor XI; deficiency occurs in cattle and dogs, causing mild to severe bleeding tendencies called hemophilia C.
  • plasma t. component (PTC) - http://www.answers.com/topic/clotting-1 factor IX; deficiency causes http://www.answers.com/topic/haemophilia-b. Called also Christmas factor, antihemophilic factor B, autoprothrombin II.
  • t. time - see http://www.answers.com/topic/activated-4 partial thromboplastin time.
  • tissue t. - factor III, a material derived from several sources in the body (e.g. brain, lung), and is important in the formation of extrinsic prothrombin converting principle in the extrinsic pathway of blood coagulation. Called also tissue factor.
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Related Questions

Why may there be large quantities of thromboplastin in blood after surgery?

why there may be large quantities of thromboplastin in blood after surgery.


What is the role of thromboplastin with anticoagulants?

n


What are the correct order of thrombin fibrin thromboplastin prothrombin and fibrinogen inblood clotting mechanism?

Thromboplastin -> Prothrombin -> Thrombin -> Fibrinogen -> Fibrin


Where is thromboplastin produced?

Thromboplastin, also known as tissue factor, is produced by subendothelial cells in blood vessel walls and by blood cells called monocytes and macrophages. Upon injury to a blood vessel, thromboplastin is exposed and initiates the extrinsic pathway of blood coagulation.


Is thromboplastin released by traumatized tissue or ruptured platelets?

True


What is a Partial thromboplastin time?

A test to check your blood clotting.


What is the function of thromboplastin in homeostasis?

In the final step of blood clotting cascade, Thromboplastin activates the prothrombin to Thrombin. Then the activated thrombin helps in the conversion of Fibrionogen into Fibrin (Mesh like fibrils which forms the clot).


Thromboplastin and PF3 interact to form?

Thromboplastin and PF3 interact to form a complex that activates the enzyme thrombin. This activation cascade is a crucial step in the blood clotting process, leading to the formation of a stable fibrin clot.


How is thromboplastin released?

Thromboplastin, also known as tissue factor, is released from damaged tissues and activated endothelial cells in response to injury. When blood vessels are damaged, the exposure of collagen and other underlying structures triggers the release of thromboplastin into the bloodstream. This protein then interacts with factor VII to initiate the extrinsic pathway of coagulation, ultimately leading to the formation of a blood clot.


When platelets rupture what enzyme is produced?

Thromboplastin (protein) your welcome. -Eli Joe


What tube would you draw an Activated Partial Thromboplastin Time in?

Light blue


What does the medical abbreviation PTT mean?

push to talk In medical settings PTT stands for partial thromboplastin time, and is a measurement of how long it takes the blood to clot.