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There are multiple medical complications associated with spina bifida, especially the most severe form (spina bifida cystica - myelomeningocele, in which a part or parts of the spinal cord protrude through the skin of the back).

With the second most common neural tube defect, anencephaly, death ensues rapidly (because the newborn cannot live for long without a brain in the skull). About three quarters of anencephalic babies do survive for a few days or even weeks (since primitive reflexes for suckling and elimination are controlled by the remaining brainstem and spinal cord).

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The risk for neural tube defects is lowered by taking supplements what type of supplement?

FOlIC ACID


Research has shown that the risk for neural tube defects decreases by including what in your diet?

Folic acid.


What trimester does neural tube defects occur?

Neural tube defects primarily occur during the first trimester of pregnancy, specifically in the early weeks shortly after conception. This critical period is when the neural tube, which eventually forms the baby's brain and spinal cord, is developing. Factors such as maternal nutrition, particularly folic acid intake, can significantly influence the risk of these defects during this time.


What is the pathophysiology of folic acid anemia?

Folic acid anemia is a known risk factor for neural tube birth defects.


Folate deficiency during pregnancy is associated with what?

Neural tube defects.


What percentage of neural tube defects is related to the mother's intake of folate before and during pregnancy?

Before the mid-1990s, about three quarters of neural tube defects could be traced to low folate levels in the mother. Since foods (mostly cereals) and prenatal vitamins now contain folate, there has been a 75% decrease in the rate of neural tube defects in the U.S. So, nowadays, the percentage of neural tube defects related to the mother's lack of folate intake is quite small, although the exact percentage has not been studied.


Is thiamin help reduce the risk of having neural tube?

Yes, thiamin (vitamin B1) plays a crucial role in overall neurological health, but the primary nutrient known for reducing the risk of neural tube defects is folic acid (vitamin B9). Adequate folic acid intake before conception and during early pregnancy is essential for proper neural tube development in the fetus. While thiamin is important for various bodily functions, including metabolism and nerve function, it is not specifically linked to neural tube defect prevention.


What are the potential consequences of a deficiency in nutrients that can lead to neural tube defects?

A deficiency in nutrients, such as folic acid, can lead to neural tube defects in babies. These defects can cause serious health issues like spina bifida or anencephaly, which can affect the brain and spinal cord development. It is important for pregnant women to ensure they are getting enough nutrients to prevent these birth defects.


Does taking folic acid reduce the risk of neural tube defects?

Yes. Vitamin B9 (Folate) deficiency can lead to neural tube defect (NTD) and the main source of it is green vegetables. That's why any woman who plans on getting pregnant should consume sufficient amounts of B9 (folic acid).


Alpha-fetoprotein in Spina Bifida?

Alpha fetoprotein is elevated when there are neural tube defects such as spina bifida.


When does spina bifida occur in pregnancy?

Spina bifida occurs during the first trimester. Spina bifida is in a class of birth defects known as neural tube defects. The neural tube eventually develops into the spinal cord, brain and the tissues that enclose them. In a normal pregnancy the tube forms early and closes by the twenty eighth day. With spina bifida portions of the neural tube fail to develop properly causing defects of varying severity in the spinal cord and back bones. This is a complicated topic and you can read more about it at the related link.


What happens if you do not get enough of folic acid?

A lack of folic acid can lead to anemia, as it is necessary for red blood cell production. Pregnant women who do not get enough folic acid are at risk for neural tube defects in their babies. Folic acid deficiency can also cause symptoms like fatigue, weakness, and difficulty concentrating.