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The A-H1N1/09 vaccine is made the exact same way as seasonal flu shots have been made for decades. Safety monitoring of those vaccines have proven them to be safe with very low adverse effects over a long period of use. There is no reason to expect that by merely using a different strain of virus in the vaccine the long term effects would be any different. That has not been the case when the strains used in the seasonal flu shots are changed each year. The human trials prior to the approval of the H1N1 vaccines proved them as safe and effective as regular seasonal flu shots. The risk of the flu is greater than any risk posed short term or long term by the vaccines to protect against it.

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