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Which antibodies initiate allergic reaction?

IgE GROUP


How do antibodies recognize antigens and initiate an immune response?

Antibodies recognize antigens by binding to specific molecules on their surface. This binding triggers a series of events that activate the immune response, including the production of more antibodies and the recruitment of immune cells to destroy the antigen.


How does the push button on the toilet operate to initiate the flushing mechanism?

When you push the button on the toilet, it activates a mechanism that releases water from the tank into the bowl, causing the toilet to flush.


Why anti-A anti-B antibodies are of class M?

Anti-A and anti-B antibodies are primarily of the IgM class because they are produced in response to exposure to A and B antigens, typically from bacteria in the gastrointestinal tract or from transfusions. IgM antibodies are the first immunoglobulins produced during an immune response and are effective in agglutinating and neutralizing pathogens due to their pentameric structure. Their large size allows them to effectively cross-link antigens on blood cells, which is crucial for the ABO blood typing system. Additionally, the presence of IgM antibodies helps to quickly initiate complement activation and enhance immune responses against foreign antigens.


What is bound to the surface of a B cell?

Antibodies are bound to the surface of a B cell. These antibodies serve as receptors that allow the B cell to recognize and bind to specific antigens. This binding process helps initiate the immune response by activating the B cell to differentiate into plasma cells that secrete antibodies.


How do antibodies work?

Function Since antibodies exist freely in the bloodstream, they are said to be part of the humoral immune system. Circulating antibodies are produced by clonal B cells that specifically respond to only one antigen (an example is a virus capsid protein fragment) . Antibodies contribute to immunity in three main ways: they can prevent pathogens from entering or damaging cells by binding to them; they can stimulate removal of a pathogen by macrophages and other cells by coating the pathogen; and they can trigger direct pathogen destruction by stimulating other immune responses such as the complement pathway. Antibodies that bind to surface antigens on, for example a bacterium, attract the first component of the complement cascade with their Fc region and initiate activation of the "classical" complement system. This results in the killing of bacteria in two ways. First, the binding of the antibody and complement molecules marks the microbe for ingestion by phagocytes in a process called opsonization; these phagocytes are attracted by certain complement molecules generated in the complement cascade. Secondly, some complement system components form a membrane attack complex to assist antibodies to kill the bacterium directly. To combat pathogens that replicate outside cells, antibodies bind to pathogens to link them together, causing them to agglutinate. Since an antibody has at least two paratopes it can bind more than one antigen by binding identical epitopes carried on the surfaces of these antigens. By coating the pathogen, antibodies stimulate effector functions against the pathogen in cells that recognize their Fc region. Those cells which recognize coated pathogens have Fc receptors which, as the name suggests, interacts with the Fc region of IgA, IgG, and IgE antibodies. The engagement of a particular antibody with the Fc receptor on a particular cell triggers an effector function of that cell; phagocytes will phagocytose, mast cells and neutrophils will degranulate, natural killer cells will release cytokines and cytotoxic molecules; that will ultimately result in destruction of the invading microbe. The Fc receptors are isotype-specific, which gives greater flexibility to the immune system, invoking only the appropriate immune mechanisms for distinct pathogens.


Which of the following initiates an attack against a specific antigen or pathogen?

Plasma Cell initiate attacks against specific antigens. Plasma cells are B cells bearing specific antibodies for binding to a specific antigen.


What is the first step of the negative feedback mechanism?

The first step of the negative feedback mechanism is the detection of a change in a physiological parameter, such as temperature or hormone levels, by specific sensors in the body. These sensors then send signals to the control center to initiate a response to counteract the change and maintain homeostasis.


What immunoglobulin is the most common in blood and initiates the complement cascade?

Both IgG and IgM initiates complement. IgG is far more abundant in the body however this does not necessarily means that it initiates complement more. IgM is the 1st immunoglobulin that responds to a foreign antigen as part of the body's hormonal response. So to answer the question directly, neither immunoglobulin initiate the complement cascade more than the other. Some research seems to indicated that there is no significant difference in ability to bind complement between IgG and IgM via the classical pathway in humans.


Can you give a sentence with the word initiate?

The council is prepared to initiate our latest initiate. "Initiate sequence!", shouted the Mission Commander.


What are the elements of bomb?

The main elements of a bomb typically include an explosive material, a triggering mechanism (such as a fuse or timer), and a containment or delivery system to focus the blast. Other components may include shrapnel, a power source for the triggering mechanism, and a detonator to initiate the explosion.


Initiate is to begin as to terminate is to what?

To initiate is to begin as to terminate is to end.