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The first claimed treatment of a cancer was performed by a medical student named Emil Grubbé at the University of Chicago on January 29, 1896. The treatment of an advanced breast carcinoma involved placing an x-ray tube against the lesion on the patient for as long as it was comfortable to the patient. Grubbé noted a marked regression of the tumor.

Reference: http://www.chi-rad-soc.org/grubbe.htm

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