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There was speculation that it may have started at an American owned pig farm in Mexico, a Smithfield Foods facility. However, the following article states that Mexico's Agriculture Department has proven it was not the original location:
Press Release from the National Pork Producers Council:
"Washington, May 14, 2009 -
Mexico's agriculture department today said the influenza strain that now has infected almost 4,300 people in 33 countries did not originate from hogs at a Smithfield Foods operation that had been singled out by some, including critics of modern pork production, as the source of the A-H1N1 flu virus.
Test results released today by the Mexican Ministry of Agriculture, Ranching, Rural Development, Fisheries and Food (SAGARPA) confirmed that the novel A-H1N1 virus was not in pigs at the Granjas Carroll de México farm in Veracruz. The pigs also tested negative for other viruses. "

The generic virus itself is not new-Swine Flu caused a brief panic in 1976 when it appeared in a U.S. army base and sickened many of the soldiers stationed there. Ironically the biggest fallout from that incident of swine flu came from the vaccine that President Gerald Ford urged citizens to get: only one person died from the actual flu while twenty-five died and five-hundred took sick from the vaccine. To further complicate our understanding of where this virus came from, researchers are now saying that "swine" flu isn't even the correct description of what this current one is, since this virus is made up from a mix of porcine, avian and human flu strains. Swine flu, in it's purely "piggy" form, is actually found in pigs worldwide, literally in every country. The World Animal Health organization is recommending the virus be renamed to "North-American influenza" to reflect its presumed origins. It is being called "Influenza A, Novel H1N1 (formerly Swine Flu)" by CDC and WHO and most of the world nations' ministries of health now.
For this particular incarnation of swine flu to transfer to humans would have taken a fairly complicated series of events. A pig with swine flu would have had to come into contact with a human with "human" flu and then the two viruses would have had to hybridize in the pig. Eventually a new strain of flu would be created that could be caught by humans, and would perhaps be carried back to humans via flies.
For a more scientific or medical explanation to answer the question, see the related answer below about the cause of the 2009 "Swine Flu" H1N1 Virus.

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