The ABO phenotype that contains the most H antigen on the red cell surface is the O phenotype, as individuals with this phenotype have the highest concentration of H antigen and lack A and B antigens. Conversely, the AB phenotype contains the least H antigen because it has both A and B antigens, which are produced by the modification of H antigen, resulting in a lower amount of unmodified H antigen on the surface.
The Bombay phenotype is caused by a homozygous recessive mutation in the FUT1 gene, which results in the absence of H antigen on red blood cells. Therefore, the genotype for the Bombay phenotype is hh.
O
A monovalent antigen is a type of antigen that contains only one type of epitope, which is the specific molecular structure that can be recognized by the immune system. This means that the antigen can only trigger a response from one type of antibody.
Antigen challenge and clonal selection are most likely to occur in the secondary lymphoid organs, such as the lymph nodes and spleen. These organs are where antigens encounter immune cells, triggering an immune response and the selection of specific immune cell clones.
Antigen-presenting cells (APCs) are nonlymphocyte cells that play a central role in clonal selection. They present antigens to T cells, triggering the immune response and selection of specific clones of T cells that can recognize and respond to the antigen.
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The clonal-selection theory posits that each lymphocyte expresses a specific receptor for a particular antigen, and upon encountering its specific antigen, it proliferates and differentiates into effector cells. A false statement about this theory might be that all lymphocytes can recognize and respond to any antigen, as the theory emphasizes that only those with the matching receptor are activated. Furthermore, it does not suggest that immune memory is formed solely from the initial response, as memory cells are also generated during the clonal selection process for future encounters with the same antigen.
The IB allele is considered dominant to the i allele because it produces a functional enzyme that adds the B antigen to the surface of red blood cells, while the i allele does not produce any antigen. This means that when both alleles are present (IBi), the B antigen is expressed, resulting in the phenotype associated with the IB allele. In contrast, the presence of the i allele does not affect the expression of the B antigen, making IB phenotypically dominant.
Clonal selection is responsible for the production of a large population of identical B or T cells that specifically recognize and target a particular antigen. This process is critical for the adaptive immune system's ability to mount a targeted immune response against pathogens.
No, B is a blood type representing the presence of the B antigen on red blood cells. It is one of the ABO blood group system classifications.
Type A, is this from the Blood Basics Quiz? I hate that thing.
Neither. Alloreactivity has to do with a lymphocytes reacting to a foreign antigen. Positive and negative selection are processes of central tolerance which is to say that they deal with a T cell's ability to bind self-antigen.