B cells do not contain any antibodies on their surface. Generally, B cells produce all the antibodies in the body is in need of; as instructed by T helper cells (CD4+ cells).
No, they are entirely two different things. What might stimulate a receptor could be an antigen.
The class of immunoglobulin to respond to the fist exposure of an antigen is immunoglobulin class M (IgM). While Immunoglobulin G (IgG) would predominate on the second exposure.
the antigen must bind to the receptor
The glycoprotein CD4 is a co-receptor. A co-receptor is "a cell surface receptor, which, when bound to its respective ligand, modulates antigen receptor binding or affects cellular activation after antigen-receptor interactions." (MediLexicon)
Question is little bit confusing. Anyway I have an answer and hope it make sense to this question. Antibodies binds to a part of an antigen which is known as Epitope.
When an antibody attaches onto an antigen it destroys the antigen to help your body fight off a disease.
The Burnet theory about antigen antibody reaction is a basic concept about how we make antibodies specific to a foreign substance which has the ability to induce an immune response (antigen). Each B cell displas one unique type of B cell receptor on their surface (which is basically a membrane bound antibody). Therefore many B cells, each expressing its own type of B cell receptor are needed to cover the inexhaustable number of antigens that are possible, in the hope that one type of B cell receptor will be able to recognise the shape of that antigen. If one B cell does recognise the antigen in question, then this B cell will become activated to make many clones of itself, which will obviously carry identical B cell recptors which fit the antigen. |Therefore the clonal selection theory by Burnet is about antibody antigen interactions which result in the 'best-fit' B cell receptor inducing a reaction to tell the B cell carrying the receptor to multiply and produce lots of identical antibodies which can then be secreted to bind to the antigen they are specific for.
Multiple antigen peptides (MAPs) consist of highly branched lysine dendrimer core and many copies of antigen peptides chemically attached to its ends
An antigen is any substance that causes your immune system to produce antibodies against it. An antigen may be a foreign substance from the environment, such as chemicals, bacteria, viruses, or pollen. It could be also called an irritant.
Helper T cells recognize the receptor-antigen complex and cause plasma and memory cells to be produced to then produce antibodies.
Naive antigen-nonspecific T cells do not become activated since they lack the T cell receptor specificity for the particular antigen being presented. They do not respond to IL-2 secreted by the activated antigen-specific T cells and remain in a resting state until they encounter an antigen to which they are specific.
Yes. The first signal that a T cell receives from an antigen presenting cell (dendritic cell) is MHC presenting an antigen (foreign peptide). This gives the T cell specificity to this antigen.