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Familial Mediterranean fever (FMF) was first described in the 1940s by Dr. Michael E. Gershoni, a physician who observed recurrent fever episodes in patients of Mediterranean descent. The condition is characterized by periodic fevers and abdominal pain due to inflammation. It was later linked to mutations in the MEFV gene, which plays a role in regulating inflammation. The discovery of the genetic basis for FMF helped improve diagnosis and treatment for affected individuals, particularly among populations in Mediterranean regions.

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6d ago

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