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Why does sickle cell hemoglobin migrate slower than normal hemoglobin during electrophoresis?
because of the change of AA- in normal cell- from Glutamic acid (negativity charged) to Valine (uncharged) -in sickle cell- the charge will be missing in the sickle cell that why the electrophoresis will become slower because of the missing charge
What is the molecular basis for the difference in the electrophoretic pattern between normal hemoglobin A and hemoglobin S?
The difference in electrophoretic pattern between normal hemoglobin A and hemoglobin S is due to a single amino acid substitution. In hemoglobin S, a glutamic acid is replaced by a valine at position 6 of the beta-globin chain. This change causes hemoglobin S to have a different charge, leading to its characteristic migration pattern on electrophoresis.
What is the name of blood test that says you are 'AA' or 'AS or'SS'?
The blood test is called a hemoglobin electrophoresis test, which is used to determine an individual's hemoglobin genotype. A result of 'AA' indicates normal hemoglobin, 'AS' indicates sickle cell trait (carrier), and 'SS' indicates sickle cell disease.
What is a the normal hemoglobin level for a baby?
For an infant, normal hemoglobin is 14-22 g/dL
What is the purpose of fetal hemoglobin test?
Fetal hemoglobin (Hemoglobin F), Alkali-resistant hemoglobin, HBF (or Hb F), is the major hemoglobin component in the bloodstream of the fetus. After birth, it decreases rapidly until only traces are found in normal.
What is the difference between normal and sickle cell hemoglobin?
loss of only one amino acid from the normal hemoglobin molecule
What are normal hemoglobin levels or amounts of iron for neonates?
Normal levels of hemoglobin for neonates are 17 - 22 g/dl.
What are normal hemoglobin levels or amounts of iron for adult females?
Normal levels of hemoglobin for adult females past menopause are 11.7 - 13.8 g/dl.
Is a hemoglobin level of 17.6 normal?
The normal hemoglobin level ranges from 12-18 grams per deciliter. Above normal hemoglobin levels may result in dehydration, excess production of rbc in bone marrow and other conditions.
What is the normal Hemoglobin or Hg in a Male patient?
Normal Hemoglobin levels in a Male is 13.8 to 17.2 gm/dL but this can vary based on various labs and what they consider to be the normal range.
What is the normal hemoglobin value percent?
For adult males the normal hemoglobin values are from 14-18 grams/deciliter. For adult females the normal hemoglobin values are from 12-16 grams/deciliter. I don't know how these values could be expressed as percents.
What is the amount of hemoglobin in a normal person?
40
