Blood Type 'O': Red Blood cells have neither A-antigen, nor B-antigen but generates both Anti-A and Anti-B antibodies -
Blood Type 'A': Red blood cells have the A-antigen which generates the Anti-B antibodies
Blood Type 'B': Red blood cells have the B-antigen and generate Anti-A antibodies
The lack of antigen explains why Type "O" can safely donate to Type "A" and Type "B". The Anti-A and Anti-B antibodies generated by Type "O" is the reason "O" cannot receive donations from Type "A" or Type "B".
the transfusion reaction doesn't occur the first time an Rh+ patient is exposed to Rh- blood because the Rh+ patients body hasn't created the antibodies needed to attack the Rh- blood that it comes in contact with. the second time the Rh+ patients body comes in contact with Rh- blood, it will have the antibodies necessary to fight against Rh- blood.
A reaction to the wrong type could be fatal.
Stop the transfusion immediately, monitor vital signs, and notify the healthcare provider. Chills and rigors during a blood transfusion could indicate a transfusion reaction which needs to be addressed promptly to prevent further complications.
1-Type A ... which has antibodies : B ... and Antigene : A2-Type B ... which has antibodies : A ... and Antigen : B3-Type AB . which has No antibodies ... and has Antigen : A and B4-Type O .. which has antibodies : A and B ... and has No Antigensfrom this information's, you can notice that AB blood type doesn't have Antibodies that's why it accept all types during blood transfusion, when there is no antibodies this means that the body will not consider the other blood types as foreigners.
transfusion is required for you. Or you will die.
During an antigen-antibody reaction, antibodies bind to antigens on the surface of pathogens, marking them for destruction. Macrophages recognize these marked pathogens and engulf them through a process called phagocytosis. The antibodies help enhance the efficiency of macrophages in clearing pathogens from the body.
Anti M antibodies can cause anemia in the mother or infant. This is a worse case scenario. Usually, the antibodies ae too large to cross over into the placenta. Antibodies levels will likely be tested monthly and a MCA Doppler ultrasound to check the baby for anemia. A blood transfusion(s) may have to be done in utero or immediately following birth.
DefinitionA hemolytic transfusion reaction is a serious problem that occurs after a patient receives a transfusion of blood. The red blood cells that were given to the patient are destroyed by the patient's own immune system.Alternative NamesBlood transfusion reactionCauses, incidence, and risk factorsBlood is classified into different blood types called A, B, AB, and O.The immune system normally can tell its own blood cells from blood cells from another person. If other blood cells enter your body, your immune system may make antibodies again them. These antibodies will work to destroy the blood cells that the body does not recognize. For example, a person with type A blood makes antibodies against type B blood cells.Another way blood cells may be classified is by Rh factors. People who have Rh factors in their blood are called "Rh positive." People without these factors are called "Rh negative." Rh negative people form antibodies against Rh factor if they receive Rh positive blood.There are also other factors to identify blood cells, in addition to ABO and Rh.Blood that you receive in a transfusion must be compatible. Being compatible means that your body will not form antibodies against the blood you receive. Blood transfusion between compatible groups (such as O+ to O+) usually causes no problem. Blood transfusion between incompatible groups (such as A+ to O-) causes an immune response. This can lead to a very serious transfusion reaction. The immune system attacks the donated blood cells, causing them to burst.Today, all blood is carefully screened. Modern lab methods and many checks have helped make these transfusion reactions very rare.SymptomsBloody urineChillsFainting or dizzinessFeverFlank pain or back painRashSymptoms of transfusion reaction usually appear during or right after the transfusion. Sometimes, they may develop after several days (delayed reaction).Signs and testsThis disease may change the results of these tests:BilirubinCBCCoombs' test, directCoombs' test, indirectFibrin degradation productsHaptoglobinHematocritHemoglobinRBC countSerum creatinineSerum hemoglobinUrinalysisTreatmentTherapy can prevent or treat the severe effects of a hemolytic transfusion reaction. If symptoms occur during the transfusion, the transfusion is stopped immediately. Blood samples from the person getting the transfusion and from the donor may be tested to tell whether symptoms are being caused by a transfusion reaction.Mild symptoms may be treated with the following:Antihistamine drugs (such as diphenhydramine) can treat itching and rash.The pain reliever, acetaminophen can reduce fever and discomfort.Corticosteroids (such as prednisone or dexamethasone) can reduce the immune response.Fluids given through a vein (intravenous) and other medications may be used to treat or prevent kidney failure and shock.Expectations (prognosis)The outcome depends on the severity of the reaction. The disorder may disappear without problems. Or, it may be severe and life threatening.ComplicationsAcute kidney failureAnemiaDiscomfortLung dysfunctionShockCalling your health care providerTell your health care provider if you are having a blood transfusion and you have had a reaction before.PreventionDonated blood is put into ABO and Rh groups to reduce the risk of transfusion reaction.Before a transfusion, patient and donor blood is tested (crossmatched) to see if it is compatible. A small amount of donor blood is mixed with a small amount of patient blood. The mixture is checked under a microscope for signs of antibody reaction.Before the transfusion is given, the health care provider will usually check again to make sure you are receiving the right unit of blood.ReferencesGoodnough L. Transfusion medicine. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 183.
No, blood cannot be drawn during a transfusion as the purpose of a transfusion is to provide blood to the patient, not to remove blood from them. Drawing blood during a transfusion would disrupt the process and potentially cause harm to the patient.
The very short answer is, badness shall ensue. People with type B blood often have circulating antibodies in their blood stream against type A antigens. If you give a person with type B blood an infusion of type A red blood cells, the person will have a transfusion reaction during which their anti-A antibodies will destroy all the red blood cells you just infused. This can be lethal, and until blood typing was well understood this often happened.
Antibodies in blood can be dangerous before surgery because they may indicate an immune response to foreign substances, such as previous infections or incompatible blood types. If transfusions are necessary during or after surgery, the presence of specific antibodies can lead to transfusion reactions, which can cause severe complications. Additionally, these antibodies may interfere with the body's healing process post-surgery. Therefore, assessing antibody levels is crucial for patient safety and optimal surgical outcomes.
It is very rare for you to have a blood transfusion. In most cases, you do not need one.