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"X-linked" disorders are more commonly observed in males do to the chromosomal make up of boys and girls. As you are probably already aware, females have two X chromosomes and no Y chromosomes. Males on the other hand have one Y chromosome and only one X chromosome.
Since this is the case, when a male receives an X chromosome with a mutation on it, they have to use that X chromosome as a "blueprint" even if the information on it is wrong. When a female has a mutation on one of her X chromosomes, she typically has another non-mutated X chromosome from which she can get the correct information.
What else can I help you with?
What allele is passed to a offspring male if mother has hemophilia?
Hemophilia is typically an X-linked recessive condition. If a mother has hemophilia, she carries two copies of the hemophilia allele on her X chromosomes (since females have two X chromosomes). Therefore, any male offspring will inherit one of her X chromosomes, which will carry the hemophilia allele, leading to him being affected by the condition. The male will inherit his Y chromosome from his father, which does not carry the hemophilia gene.
Are some boys carriers for hemophilia?
A male with hemophilia does in fact carry the genes and can pass them on to his daughters, so yes, some boys (if they have hemophilia) are carriers.
The hereditary disease in which clotting does not occur is known as?
hemophilia
What are the statistics of hemophilia?
1 in 5,000 male birth
Is hemophilia mostly seen in males?
Yes. Mostly males. It is exceedingly rare for a woman to acquire hemophilia(unless she is a carrier of it). Women have a diminutive chance of having this genetic disorder.
What chromosomes does hemophilia occur on?
Hemophilia is a X linked recessive disorder. Usually the mother is an unaffected carrier and her son unfortunately receives the X chromosome in which hemophilia is linked to.
Why Hemophilia more common in male than in female?
The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.
What gene does hemophilia affect?
The gene that causes hemophilia is located on the X chromosome. A woman who gives birth to a child with hemophilia often has other male relatives who have hemophilia. Sometimes, a baby will be born with hemophilia when there is no known family history. This means the gene can be"hidden"( or passed down through several generations of female carriers without affecting any male members of the family) or the change in the X chromosome is new (a spontaneous mutation).
How can a lady have hemophilia will it effect menstrual period?
Normally a woman is only a carrier of hemophilia, but if her mother is a carrier and her father has hemophilia the female does have a chance to get it. It is very rare for this to happen but It has been recorded.
Can you develop hemophilia later in life?
Yes, it is possible to develop hemophilia later in life, although it is rare. Acquired hemophilia can occur in adults due to certain medical conditions or medications that interfere with the body's ability to clot blood.
Does hemophilia occur more often in a certain blood type?
Hemophilia does not occur more frequently in any specific blood type. It is a genetic disorder primarily linked to mutations in the genes responsible for producing clotting factors, particularly factor VIII (hemophilia A) and factor IX (hemophilia B). The condition is inherited in an X-linked recessive manner, meaning it predominantly affects males regardless of their blood type. Therefore, blood type does not influence the incidence of hemophilia.
Why is hemophilia considered to be a sex link trait?
Because the gene that causes hemophilia is located on the X chromosome, so it will occur in males more frequently than in females.
