While the kidney is normally thought of as an excretory organ, it is also an important endocrine organ (ie, one that produces hormones). One of the hormones it produces is called erythropoietin (EPO), which stimulates the production of red blood cells (RBCs). RBCs are basically sacs of hemoglobin that carry oxygen around. The amount of hemoglobin varies according to the number of RBCs in the blood. And the number of RBCs in the blood is controlled by EPO. In kidney disease, EPO production decreases because the kidney is malfunctioning. As a result, RBC count decreases, as does hemoglobin.
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This information can be used to help physician's diagnose and monitor anemia (a low hemoglobin level) and polycythemia vera (a high hemoglobin level).
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Low hemoglobin level
A hemoglobin level of 4.7 is dangerously low and if not properly treated could become fatal. Normally, women should have a hemoglobin level of 12 or more, men 13 or more. Generally, hospitals will begin emergency blood transfusions when the hemoglobin level drops below 7 or 8.
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Since erythropoietin is synthesized in the kidney, the effect of kidney failure is to depress red blood cell production. Thus, anemia occurs. The average hemoglobin level for an individual suffering from ESRD (end stage renal disease) is no more than 10.8 in the vast majority of cases.
Nephritis is inflammation of the kidney. About half of all lupus patients have lupus nephritis (kidney disease). A kidney biopsy is done to determine which classification and which level so that appropriate treatment can be prescribed. There are six World Health Organization classificationsfor lupus nephritis with the first one being "no disease."
For an infant, normal hemoglobin is 14-22 g/dL
There is no correlation between hemoglobin and lung cancer. A high or low hemoglobin can mean any number of conditions; people with lung cancer can have any level of hemoglobin depending on situation and other conditions.
Creatinine clearance is a measure of kidney function. Patients are on dialysis because their kidneys do not function properly thus their creatinine clearance would be very, very low. Some patients may have some residual kidney function but their creatinine clearance would be less than probably 10 ml/min.