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Typhus is caused by bacteria of the genus Rickettsia, which are classified as gram-negative due to their cell wall structure. Gram-negative bacteria have a thin peptidoglycan layer and an outer membrane containing lipopolysaccharides, which do not retain the crystal violet stain used in the Gram staining procedure. This characteristic is important for identifying the bacteria and understanding their pathogenic mechanisms. Additionally, the outer membrane contributes to their resistance to certain antibiotics and immune responses.

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3d ago

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