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After the war between (China Opium War), which was the source of the Black Death or plague that killed over 1/3 of Europe's population. The rats had gotten it, the fleas had gotten, the people had gotten it.

Europe had to be the nation that got it the worst because of unsanitary acts.

It was easily spread by people coughing, not washing hands, and contact between people as the plague spread violently and quickly.

There was no treatment, so there was no window of hope.

Flea bites where absolutely everywhere.

Basically a breath breathed and the windows close.

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