0
Dubin-Johnson syndrome is a disorder passed down through families (inherited) in which a person has mild jaundice throughout life.
Causes, incidence, and risk factorsDubin-Johnson syndrome is a very rare genetic disorder. In order to inherit the condition, a child must get a copy of the defective gene from both parents.
The syndrome interferes with the body's ability to move bilirubin from the liver. Bilirubin is produced when the liver breaks down worn-out red blood cells. It normally moves through the bile produced by the liver and into the bile ducts, past the gallbladder, and into the digestive system.
When bilirubin is not properly processed, it builds up in the bloodstream and causes the skin and the whites of the eyes to turn yellow (jaundiced). Severely high levels of bilirubin can damage the brain and other organs.
People with Dubin-Johnson syndrome have lifelong mild jaundice that may be made worse by:
- Alcohol
- Birth Control pills
- Infection
- Other environmental factors that affect the liver
- Pregnancy
Mild jaundice, which may not appear until puberty or adulthood, is the only symptom of Dubin-Johnson syndrome.
Signs and testsThe following tests can help diagnose this syndrome:
TreatmentNo specific treatment is required.
Expectations (prognosis)The outlook is very positive. Dubin-Johnson syndrome generally does not shorten a person's life span.
ComplicationsComplications are unusual but may include the following:
- Severe jaundice
- Reduced liver function
Call your health care provider if any of the following occurs:
- Jaundice is severe.
- Jaundice gets worse over time.
- Abdominal painor other symptoms are also present (may indicate another disorder is causing the jaundice).
Genetic counseling may be helpful for people who wish to have children and have a family history of Dubin-Johnson syndrome.
What else can I help you with?
What is syndactyly a symptom of?
Syndactyly is a characteristic of Apert syndrome, Poland syndrome, Jarcho-Levin syndrome, oral-facial-digital syndrome, Pfeiffer syndrome, and Edwards syndrome
Which syndrome is the complete opposite of Lima syndrome?
Stockholm syndrome.
What other conditions could an infant with syndactyly have?
Syndactyly is a characteristic of Apert syndrome, Poland syndrome, Jarcho-Levin syndrome, oral-facial-digital syndrome, Pfeiffer syndrome, and Edwards syndrome.
Is xxxy syndrome barr-shaver-carr syndrome?
XXXY Syndrome and Barr-Shaver-Carr Syndrome are the same.
What is the medical term meaning the result of prolonged exposure to high levels of cortisol?
Cushing's Syndrome
What is a chromosomal disorder that could result from nondisjunction?
Disorders, such as Down's Syndrome, are caused by nondisjunction.
Klinefelter syndrome is what?
what is kinefelter syndrome?
Is there such a syndrome as 9p syndrome?
yes there is.
Is Angelman syndrome the same as Down syndrome?
Angelman syndrome is a genetic disorder, as is Down syndrome. But they are not the same. Angelman Syndrome involves a deletion of Chromosome 15, whereas people with Down syndrome have an extra copy of Chromosome 21.
By what other names is fragile X syndrome known?
also known as Martin-Bell syndrome, Marker X syndrome, and FRAXA syndrome
Is Down syndrome the same as Cohen syndrome?
no
What is all ports syndrome?
Alport Syndrome
