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I am a pharmacist and have seen the two used together...Cymbalta is a SNRI and can sometimes cause insomnia (usually used once daily). Prescribers may add trazodone once nightly and it is helpful for this side effect caused by Cymbalta.

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17y ago

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Can you take trazodone while taking Prozac?

Yes, if both are prescribed for you, there is no problem in taking those 2 drugs together. To get the "sleeping" effect of trazodone, without interfering with prozac antidepressant effect, the trazodone dosage should be around 25mg to 100mg.


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