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I would venture to say that you shouldn't combine these drugs without checking with your pharmacist first. For your own health I would advise this. However, seeing that ibuprofen is an NSAID (designed to relieve muscle pain by reducing inflammation) and that Oxycodone/APAP (Percocet) is an analgesic, there is no pharmacological reason that THESE cannot be used with each other. However, cephalexin is an antibiotic and may reduce the effectiveness of the Percocet/IB combination, or worse, have adverse reactions such as liver damage or respiratory depression (slowing of breathing caused by too much depressent). I would ask a pharmacist before taking anything. If he gives you the all clear, then by all means go for it. If not, don't do it. Period.

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16y ago

What else can I help you with?