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Yes. They are from different drug classes and have different effects. Wellbutrin is an anti-depressant of the Dopamine Norepinephrine Reuptake Inhibitor class. Ativan is an anxyolitic drug and is a benzodiazepine. I use this combination - wellbutrin daily, and ativan as needed for anxiety and insomnia. It works well.

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Update: I must disagree with the answer above (whoever wrote it). If you look up Bupropion (a.k.a. Wellbutrin) on Wikipedia, then scroll down to "Contraindications", it states clearly that Wellbutrin should not be taken with any type of benzodiazepine (which is what Lorazepam - a.k.a. Ativan - is). So you should absolutely talk this over with a doctor instead of asking the internet. You might just get an "I don't see why not" guess from someone who may not truly know the answer. Bottom line - talk to your doctor before taking those two together!

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10y ago

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