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Depends on whether or not you are using these two recreationally or not. For the record, I don't advocate that, seeing as I almost overdosed and died on Delsym a few years ago. If you are using these two drugs as they are intended to be taken, Delsym should not be taken with Oxycodon, or any kind of opiate, mostly because the DXM in Delsym will not mix well with the painkilling effects of Oxycodon. Oxycodon is an extremely powerful painkiller and should never be taken with any other medication - the side effects are too pronounced. If you are using these two substances recreationally, never, ever, under any circumstances mix the two. High doses of Delsym will spike your blood pressure to unhealthy extremes, and can lead to heart palpitations and even trouble walking. Adding Oxycodon to this mix will worsen these symptoms and could possibly cause trouble breathing. I am not a doctor, so I can't give you all the medical jargon, but as a former experimental moron, I can tell you that mixing these two substances is not recomended.

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16y ago

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