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I use Lunesta quite often. I have used it along side "Advil" (ibuprofen) and have noticed very little. If anything, I would say that the Ibuprofen takes away from the effects of the Lunesta, I continue to seek the proper resolution, but I have yet to think that there is any major impact. If I should find another conclusion, I will let you know.

So, to answer your question, no, there isn't any issue taking Ibuprofen with Lunesta.

*I'm no doctor, please consult them before you take any of my advice*

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17y ago

What else can I help you with?