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Yes, you can. Acetaminophen (Tylenol) works on a different part of the body than NSAID Drugs (Non-Steroidal Anti-Inflammatory Drugs). In fact, there is a study being performed in New Zealand to show the effect of taking an NSAID with acetaminophen (the study was performed with ibuprofen, but naproxen sodium and ibuprofen are in the same class of medication). The drug, marketed as Maxigesic, includes 500 milligrams of paracetamol (acetaminophen) and 150 milligrams of ibuprofen, and found no drug interaction. In fact, the study found the combination of acetaminophen and an NSAID drug improved the analgesic effect (pain relieving effect) by up to 37% (see references below). Additionally, Drugs.com shows no drug interactions between Aleve and Tylenol (naproxen sodium and acetaminophen).

Please be aware that both acetaminophen and naproxen sodium are contraindicated for certain individuals. Acetaminophen has been shown to cause liver damage at high dosages, and NSAID drugs, including Aleve and Advil, can cause severe stomach bleeding. Both of these conditions can be fatal. Those with liver damage should not take acetaminophen, and anyone with a history of stomach bleeding, or that has a risk of stomach bleeding, should not take NSAID drugs, including Aleve or Advil.

NOTE: I am not a doctor or a pharmacist. Please speak to a licensed doctor or pharmacist before taking any medication, whether over the counter or prescription.

References:

http://www.medsafe.govt.nz/profs/datasheet/m/maxigesictab.pdf (Data sheet about Maxigesic)

http://www.drugs.com/drug-interactions/aleve-with-tylenol-1690-2475-11-12.html (Drug interaction report from Drugs.com showing no interaction between Aleve and Tylenol).

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12y ago

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