Cyclizine degrades primarily through hydrolysis and oxidative processes, which can be influenced by factors such as pH, temperature, and light exposure. In aqueous solutions, cyclizine may undergo hydrolytic breakdown, leading to the formation of various metabolites. Additionally, exposure to oxidative agents can facilitate further degradation, resulting in the loss of its pharmacological activity. The specific pathways and rates of degradation can vary depending on the environmental conditions.
can you take cyclizine hydrochloride when pregnant?
Cyclizine is used for motion sickness and vomiting. It is taken 30 minutes before departure and can be repeated every four to six hours as needed.
Cyclizine works by blocking histamine receptors in the brain, which helps to prevent or relieve symptoms of nausea and vomiting. It also has anticholinergic properties, which contribute to its antiemetic effects.
the only difference i found was that meclizine is not given to < 12 year old, only to 12 and older. cyclizine is given to age 6-12 and not <6 years old.
Bonine for kids @ Shopko, ShopRite(.com), Amazon.com (Cyclizine Hcl 25mg) about $4 for 8 chewable tablets Marezine @ Amazon.com, MyOTCStore.com (Cyclizine Hcl 50mg) about $80 for 100 tablets
pKa1 = 2.16 pKa2 = 8.05 Ref: Newton, D.W., Murray, w.j., Lovell, M.W. pKa Determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions (1982) Journal of Pharmaceutical Scienses 71 (12), pp. 1363-1366
Cyclizine tablets are not intended for injection, and it is unsafe to prepare them for this purpose. The formulation of tablets is different from that of injectable medications, and improper preparation can lead to severe adverse reactions or complications. If injectable cyclizine is needed, it is essential to use a commercially available injectable formulation prescribed by a healthcare professional. Always consult a qualified medical provider for appropriate medication administration.
no! it causes the cyclizine to precipiate out of solution and blocks lines either iv or subcut. this can cause unnecessary stress and anguish to the patient as lines are required more often etc, use water for injection instead or a low % dextrose solution. if using a syringe driver water for injection MUST be used rather than saline otherwise your causing unnecessary distress to your patient as lines get needing changing more frequently. hope that helps, sammy
if the case is serious , and take promotion from physican
Answer: No drug should ever be combined with any other drug without the expresss knowledge and consent of a doctor.
Cyclizine is typically administered orally, but it can be given rectally if necessary, particularly in patients who cannot take medications by mouth. However, it's important to consult a healthcare professional before administering it this way, as rectal formulations may not be standardized, and proper dosing and absorption can vary. Always follow medical guidance for alternative routes of administration.
According to SOWPODS (the combination of Scrabble dictionaries used around the world) there are 5 words with the pattern -Y--IZ---. That is, nine letter words with 2nd letter Y and 5th letter I and 6th letter Z. In alphabetical order, they are: cyanizing cyclizine cyclizing kyanizing mythizing