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Cyclizine degrades primarily through hydrolysis and oxidative processes, which can be influenced by factors such as pH, temperature, and light exposure. In aqueous solutions, cyclizine may undergo hydrolytic breakdown, leading to the formation of various metabolites. Additionally, exposure to oxidative agents can facilitate further degradation, resulting in the loss of its pharmacological activity. The specific pathways and rates of degradation can vary depending on the environmental conditions.
What else can I help you with?
Can you take cyclizine when pregnant?
can you take cyclizine hydrochloride when pregnant?
When should you take cyclizine?
Cyclizine is used for motion sickness and vomiting. It is taken 30 minutes before departure and can be repeated every four to six hours as needed.
How does cyclizine work?
Cyclizine works by blocking histamine receptors in the brain, which helps to prevent or relieve symptoms of nausea and vomiting. It also has anticholinergic properties, which contribute to its antiemetic effects.
What is the difference between cyclizine and meclizine?
the only difference i found was that meclizine is not given to < 12 year old, only to 12 and older. cyclizine is given to age 6-12 and not <6 years old.
Is lorazepam and cyclizine given together?
Lorazepam and cyclizine can be given together, but this should be done with caution and under medical supervision. Lorazepam is a benzodiazepine used for anxiety and sedation, while cyclizine is an antihistamine used for motion sickness and nausea. Combining these medications may increase the risk of sedation and drowsiness. Always consult a healthcare provider before combining medications.
Is meclizine over the counter?
Bonine for kids @ Shopko, ShopRite(.com), Amazon.com (Cyclizine Hcl 25mg) about $4 for 8 chewable tablets Marezine @ Amazon.com, MyOTCStore.com (Cyclizine Hcl 50mg) about $80 for 100 tablets
What is the pka of cyclizine?
pKa1 = 2.16 pKa2 = 8.05 Ref: Newton, D.W., Murray, w.j., Lovell, M.W. pKa Determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions (1982) Journal of Pharmaceutical Scienses 71 (12), pp. 1363-1366
How do you prepare cyclizine tablets for injection?
Cyclizine tablets are not intended for injection, and it is unsafe to prepare them for this purpose. The formulation of tablets is different from that of injectable medications, and improper preparation can lead to severe adverse reactions or complications. If injectable cyclizine is needed, it is essential to use a commercially available injectable formulation prescribed by a healthcare professional. Always consult a qualified medical provider for appropriate medication administration.
Can you take cyclizine with trazadone hydrochloride anti depressents?
Cyclizine is an antihistamine used to treat nausea and motion sickness, while trazodone is an antidepressant commonly prescribed for depression and anxiety. Generally, there are no direct interactions between cyclizine and trazodone; however, both can cause sedation and dizziness. It is essential to consult a healthcare provider before combining these medications to ensure safety and monitor for any potential side effects.
Can you mix cyclizine with saline?
no! it causes the cyclizine to precipiate out of solution and blocks lines either iv or subcut. this can cause unnecessary stress and anguish to the patient as lines are required more often etc, use water for injection instead or a low % dextrose solution. if using a syringe driver water for injection MUST be used rather than saline otherwise your causing unnecessary distress to your patient as lines get needing changing more frequently. hope that helps, sammy
Can you take codeine paracetamol and cyclizine together?
Yes, you can generally take codeine, paracetamol, and cyclizine together, as they serve different purposes: paracetamol is a pain reliever, codeine is an opioid pain medication, and cyclizine is an antiemetic used to prevent nausea and vomiting. However, it is crucial to follow the recommended dosages and consult a healthcare professional before combining these medications to avoid potential side effects or interactions. Always consider personal health conditions and any other medications being taken.
Can you have cyclizine 50mg iv more then 3 times a day for anti-sickness?
if the case is serious , and take promotion from physican
