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Depakote (divalproex sodium) and caffeine can interact, although the effects may vary among individuals. Caffeine may potentially decrease the effectiveness of Depakote by increasing metabolism and clearance of the medication, which could lead to lower levels in the bloodstream. However, there is no significant direct interaction, so moderate caffeine consumption is generally considered safe for most patients taking Depakote. It's always best to consult a healthcare provider for personalized advice.

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1mo ago

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