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It's best to wait until the ibuprofen clears your system in 6-8 hours (especially if you are using prescription level Ibuprofen). Ibuprofen can be a irritant to the GI tract, and can sometimes cause bleeding, and alcohol only increases this risk. Ibuprofen also inhibits the liver's functions as well, so you would only be compounding that effect by adding alcohol.

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16y ago

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