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The over-the-counter maximum daily dose of ibuprofen is 1200 mg/day. Long term use of even the maximum amount is associated with certain health risks (such as GI bleeding and kidney damage). There are some disease states which require high doses of anti-inflammatory medications for treatment. If you are currently taking ibuprofen as directed by your doctor, you will probably be fine. If this is so, it is important that you see your doctor regularly so that he/she can monitor the effects of the drug on your body (i.e. blood tests to assess kidney function, etc). Your doctor may choose to prescribe a prophylactic dose of a proton pump inhibitor (Nexium, Prilosec, Protonix, Aciphex) or H2 antagonist (Zantac, Pepcid, Tagamet) to prevent an NSAID induced ulcer. If you have heartburn-like symptoms or notice that you bleed/bruise easily, feel exteremely fatigued, or have bloody or "black as coal" stools, see your doctor immediately.

If, however, you are taking 1600 mg/day longterm and are not under a doctor's care, your risk of eventually having these side effects is high. It is important that you let your doctor know that you are needing to take this much. Whatever problem is causing you to need to take this amount of ibuprofen on a regular basis should be addressed by a doctor.

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17y ago

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