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Oxycodone vs oxycodone with acetaminophine are essentially the same thing. The narcotic in both medications is the oxycodone, the only difference between the two is the addition of Tylenol (aka acetaminophen). The addition of Tylenol does not necessarily make the combo drug more powerful than the straight oxycodone, but is an adjunctive therapy so to speak. The Tylenol can enhance the pain relief of the oxycodone by working with the oxycodone at pain receptors. So to answer the question, no - oxycodone is not stronger than oxycodone acetaminophen combo.

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15y ago

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