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Both have 10 MG's of Oxycodone while the 350 and 325 refer to Tylenol or Aspirin products that have been added so 10-350 lets say has 10 MG's of Oxy. and 350 MG of Tylenol. 10-325 has 10 MG Oxy. and 325 MG of Tylenol for example.

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