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Problems occured in formulation of olopatadine and fluticasone propionate nasal spray?
Olopatadine is having pH dependent solubility and at concentration above 0.3%, it would require formulation pH below 4.
Fluticasone is water insoluble and to have proper suspension if suspending agents used, it will result in phase separation at high concentration of Olopatadine and low pH.
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What is systemic approach?
System approach allows for formulation of problems in applied sciences. In addition, it allows for effective strategy for studying the problems.
What has the author George C Georges written?
George C. Georges has written: 'Lagrangian and Hamiltonian formulation of plasma problems'
Why are conceptual skills so important?
Conceptual skills could be defined as " involving the formulation of ideas. Managers understand abstract relationships, develop ideas, and solve problems creatively."
Why doesnt the policy cycle work well for wicked problems?
The policy cycle is a linear model that involves problem definition, policy formulation, implementation, and evaluation. Wicked problems are complex, interconnected, have no clear solution, and involve multiple stakeholders. The policy cycle's linear approach does not account for the dynamic and unpredictable nature of wicked problems, making it ineffective in addressing their complexity.
How do physicists solve problems?
Physicists, along with other scientists, use the scientific method. This method consists of: Formulation of a question, Hypothesis, Prediction, Testing, and Analysis. Keep in mind that some people change the order sometimes.
What is meant by a million dollar question in mathematics?
The Clay Mathematics Institute of Cambridge, Massachusetts has named seven "Millennium Prize Problems," selected by focusing on important classic questions in mathematics that have resisted solution over the years. A $7 million prize fund has been established for the solution to these problems, with $1 million allocated to each. The problems consist of the Riemann hypothesis, Poincaré conjecture, Hodge conjecture, Swinnerton-Dyer Conjecture, solution of the Navier-Stokes equations, formulation of Yang-Mills theory, and determination of whether NP-problems are actually P-problems.
Were there any problems on the Mayflower?
Yes, there were several problems on the Mayflower. The ship was overcrowded with around 102 passengers, leading to unsanitary conditions and limited space. There were also storms that damaged the ship, causing leaks and making the journey more difficult. Additionally, there was tension and disagreement among the passengers, which resulted in the formulation of the Mayflower Compact to establish order and unity.
What is the formulation of the minimum cut linear program and how is it used in network flow optimization problems?
The minimum cut linear program is a mathematical model used to find the smallest set of edges that, when removed from a network, disconnects it into two separate parts. This model is used in network flow optimization problems to determine the most efficient way to route flow through a network by identifying the bottleneck edges that limit the flow capacity.
What is scientific problem?
A scientific problem is a question or issue that requires investigation, experimentation, or analysis to find an answer or solution. It typically involves observation, collection of data, formulation of a hypothesis, and testing to reach a conclusion based on evidence. Identifying scientific problems helps drive research and expand our understanding of the natural world.
What has the author Christine M Belcastro written?
Christine M. Belcastro has written: 'On the numerical formulation of parametric linear fractional transformation (LFT) uncertainty models for multivariate matrix polynomial problems' -- subject(s): Linear transformations, Control systems design, Direct numerical simulation, Matrices (Mathematics), Mathematical models, Robustness (Mathematics), Computerized simulation 'A problem formulation for glideslope tracking in wind shear using advanced robust control techniques' -- subject(s): Mathematical models, Air traffic control, Vertical wind shear, Wind shear
What is the relationship between the Lagrangian and Hamiltonian formulations in classical mechanics?
In classical mechanics, the Lagrangian and Hamiltonian formulations are two different mathematical approaches used to describe the motion of a system. Both formulations are equivalent and can be used interchangeably to solve problems in mechanics. The Lagrangian formulation uses generalized coordinates and velocities to derive the equations of motion, while the Hamiltonian formulation uses generalized coordinates and momenta. The relationship between the two formulations is that they both provide a systematic way to describe the dynamics of a system and can be used to derive the same equations of motion.
How is a problem different from hypothesis?
A problem is a situation that presents difficulty or challenge, while a hypothesis is a proposed explanation or prediction based on limited evidence. Problems require solving and can lead to the formulation of hypotheses as part of the problem-solving process.
