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Dependence and Tolerance are the most common, but that's true with many drugs that require long term maintenance doses. I've used them for 9 years now, and I've learned how to lower my dosages if I need to after I've had to increase them. My normal dose is 100 mcg, but I do occasionally need to increase it to 200mcg.

Duragesic is well tolerated over time. Most of the time I forget I'm wearing them, and the effectiveness cannot be overstated. For long term chronic pain, there is no better drug.

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16y ago

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