Lexapro, also known as Escitalopram is an antidepressant which blocks specific potassium channels in the CNS. While most specific to the HERG channel (Kv11.1) it has also been shown to effect Kv2.1 and Kv2.2 as well as Kv1.5 potassium channels
The channels that transport sodium and potassium within the axon are called voltage-gated sodium channels and voltage-gated potassium channels. These channels play a crucial role in generating and propagating action potentials along the axon.
Increasing extracellular potassium ion concentration will create a smaller concentration gradient across the cell membrane, making it less favorable for potassium ions to move out of the neuron through the leak channels. The leak channels are gated by both membrane voltage and concentration gradients, so alterations in extracellular potassium levels can impact the electrochemical equilibrium that regulates potassium movement. Ultimately, this can result in a reduced net diffusion of potassium ions out of the neuron.
Voltage-gated potassium channels open immediately after the action potential peak, allowing potassium ions to exit the cell. This repolarizes the cell membrane and helps bring it back to its resting state.
Potassium efflux is controlled by voltage-gated potassium channels, while sodium influx is controlled by voltage-gated sodium channels. These channels open and close in response to changes in membrane potential, regulating the flow of ions in and out of the cell.
The potassium ion is responsible for depolarization of hair cells in the spiral organ. When deflected, potassium channels open, leading to an influx of potassium ions into the cell and depolarization of the cell membrane.
Sodium, potassium, and chloride ions pass through the cell membrane via ion channels. These channels are proteins that create a passageway for the ions to move down their concentration gradients. Different ion channels have specific selectivity for certain ions, allowing them to pass through the membrane.
In the membrane of olfactory receptor neurons, passive channels such as cyclic nucleotide-gated channels and calcium-activated chloride channels are commonly found. These channels play a role in odorant detection by allowing ions like Na+ and Ca2+ to flow into the cell in response to odorant binding, which triggers the neuronal signal cascade.
The correct name for the potassium ion is simply "potassium ion."
It is called depolarization and happens when sodium and/or calcium ions enter the cell rapidly through their respective voltage-dependent ion channels or potassium ions stop leaving the cell through their ion channels or chloride ions stop entering the cell through their ion channels.
The potassium ion channels in the cell open with hyperpolarization (injecting a negative current to take the cell potential more negative than Ek) The potassium ion channels in the cell open with hyperpolarization (injecting a negative current to take the cell potential more negative than Ek)
Sodium and potassium ions do not diffuse in equal numbers through ligand-gated cation channels because these channels have different selectivity for sodium and potassium ions. The channels may have a higher affinity for one ion over the other, leading to greater permeability to that specific ion. Additionally, the concentration gradient of each ion also plays a role in determining their relative movement through the channels.
The potassium ion is K+ and the sulfate ion is SO42-