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the more ionized the drug is the less absorption

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13y ago

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What is the effect of decreased albumin concentration on drug's absorption?

The effect of decreased albumin concentration on drug absorption is that it may cause first-pass metabolism. This may increase gastric pH levels as well.Ê


Correlation between Ph Pka and absorption of drug?

pKa of a drug is the pH at which the drug is 50% ionized and 50% non-ionized. This can affect drug absorption as the ionized form may have different solubility and permeability properties compared to the non-ionized form. Understanding the pKa of a drug can help predict its behavior in different pH environments and optimize absorption.


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if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.


What is pharmacokinetic interaction?

Any medicine or drug that can interfere in absorption, distribution, metabolism and excretion of drugs and alter their original effect is call pharmacokinetic interactions.


Process that brings a drug from the administration site into the blood stream is called?

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Is pH the same thing as a drug?

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A drug has pKa 5. at which PH it will be 99.9 percent ionized?

To determine at which pH a drug will be 99.9% ionized, we need to consider the Henderson-Hasselbalch equation. The pH at which a drug is 99.9% ionized can be estimated by finding the pH value that is one unit above the pKa of the drug. Therefore, in this case, the drug will be 99.9% ionized at a pH of 6.


Why do farmers have to pay attention to pH?

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