Veterinary drug absorption is the uptake of a drug after administration so that it can cause some sort of alteration in the body.
Donald C. Plumb has written: 'Veterinary Drug Handbook/Desk' 'Veterinary drug handbook' -- subject(s): Veterinary drugs, Handbooks, manuals, etc, Veterinary pharmacology, Handbooks, manuals 'Veterinary Drug Handbook'
the more ionized the drug is the less absorption
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
Leo Meyer Jones has written: 'Veterinary pharmacology and therapeutics' -- subject(s): Drug therapy, Pharmacology, Poisoning, Veterinary, Veterinary drugs, Veterinary pharmacology, Veterinary Drugs
The process that brings a drug from the administration site into the bloodstream is called absorption. It refers to the movement of a drug from its site of administration into the bloodstream for distribution throughout the body. Factors such as route of administration, drug formulation, and physiological properties can affect drug absorption.
decrease
pKa of a drug is the pH at which the drug is 50% ionized and 50% non-ionized. This can affect drug absorption as the ionized form may have different solubility and permeability properties compared to the non-ionized form. Understanding the pKa of a drug can help predict its behavior in different pH environments and optimize absorption.
Probenecid (a drug treating gout) impairs riboflavin absorption, and propantheline bromide (a drug treating peptic ulcers) reportedly both delays and increases absorption.
Drug absorption through the skin, also known as transdermal absorption, occurs when a drug penetrates the skin layers and enters the bloodstream. Factors that influence this process include the drug's molecular size, lipophilicity (ability to dissolve in fats), skin thickness, blood flow to the skin, and the presence of enhancers or barriers on the skin.
time when drug is fully available at the max (when the absorption rate and elimination rate of the drug equals)
the kidney. not sure why
The effect of decreased albumin concentration on drug absorption is that it may cause first-pass metabolism. This may increase gastric pH levels as well.Ê